Browsing by Subject "Aging"
Now showing items 21-31 of 31
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Policy Reforms Targeting Care for Older Adults in Lithuania
(East Carolina University, 2011)This thesis project investigates policy reforms surrounding the care of older people in post-socialist Lithuania. It is argued that institutional arrangements inherited from the socialist era were shaped by indigenous ... -
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance
(2012-10)The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, ... -
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health
(2011-03)The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, ... -
The relationship between visual steadiness and force steadiness in young and old adults
(East Carolina University, 2013)Old adults exhibit a decrease in muscle force steadiness and visual capability compared to young adults. Many studies investigating force steadiness have used a visual target as the stimulus for modulating muscle force. ... -
Skeletal Muscle Forkhead Box 3A (FOXO3A) Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2010)In addition to suppressing protein synthesis, 5'-AMP-activated protein kinase (AMPK) stimulates muscle protein degradation through forkhead box transcription factor 3A (FOXO3A), known to promote transcription of mRNAs ... -
STRIDE LENGTH MANIPULATION IN YOUNG AND OLD ADULTS DURING LEVEL WALKING
(East Carolina University, 2010)Physiological and neurological changes with healthy aging cause old adults to alter biomechanical gait strategies. Mechanical plasticity is an ambulatory strategy in which old adults rely on proximal musculature in ... -
Structural aging of the utricular macula in mice
(East Carolina University, 2012)CBA/CaJ is a mouse strain that has no known genetic mutations affecting the inner ear, thereby serving as a control model for auditory and vestibular aging. C57BL/6J and CE/J mouse strains carry the genetic mutation ... -
THE EFFECTS OF AGING ON COGNITIVE MOTOR CONTROL
(East Carolina University, 2019-07-30)Introduction: Processing speed, working memory capacity, inhibitory function, and long-term memory are all aspects of information processing that become less efficient with age. Unsurprisingly, brain size, density, and ... -
The Effects of Aging on Cognitive Motor Control:Functional Connectivity Analysis of Alpha Frequency
(East Carolina University, 2021-05-28)Aging is a natural phenomenon that occurs among humans and can lead to a wide variety of physical and mental changes in individuals. Over 20 percent of the US population is projected to be age 65 and older by the year 2030. ... -
THE VARIATION IN STRENGTH DECREMENT OF LOWER EXTREMITY MUSCLE GROUPS AND BIOMECHANICAL PLASTICITY IN OLDER ADULTS
(East Carolina University, 2019-08-13)Age-associated biomechanical plasticity (BP) has been established as the distal to proximal shift of joint mechanical output in old adults while walking. The cause of BP is still unknown, but changes in muscle strength of ...