Browsing by Author "Culver, Daniel A."

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  • Gene-environment interactions in sarcoidosis 

    Culver, Daniel A.; Newman, Lee S.; Kavuru, Mani S. (East Carolina University, 2007-05)
    Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any ...

  • Peroxisome Proliferator-Activated Receptor-γ Regulates the Expression of Alveolar Macrophage Macrophage Colony- Stimulating Factor 

    Bonfield, Tracey L.; Thomassen, Mary Jane; Farver, Carol F.; Abraham, Susamma; Koloze, Mary T.; Zhang, Xia; Mosser, David M.; Culver, Daniel A. (East Carolina University, 2008-07-01)
    Macrophage CSF (M-CSF) regulates monocyte differentiation, activation, and foam cell formation. We have observed that it is elevated in human pulmonary alveolar proteinosis (PAP) and in the GMCSF knockout mouse, a murine ...