Browsing by Author "Fan, Junming"
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Claudin-7 Modulates Cl− and Na+ Homeostasis and WNK4 Expression in Renal Collecting Duct Cells
Fan, Junming; Tatum, Rodney; Hoggard, John; Chen, Yan-Hua (2019-07-30)Claudin-7 knockout (CLDN7−/−) mice display renal salt wasting and dehydration phenotypes. To address the role of CLDN7 in kidneys, we established collecting duct (CD) cell lines from CLDN7+/+ and CLDN7−/− mouse kidneys. ... -
A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
Lu, Zhe; Kim, Do Hyung; Fan, Junming; Lu, Qun; Verbanac, Kathryn; Ding, Lei; Renegar, Randall; Chen, Yan-Hua (2015-06-17)Background Claudins are a family of tight junction (TJ) membrane proteins involved in a broad spectrum of human diseases including cancer. Claudin-7 is a unique TJ membrane protein in that it has a strong basolateral ...