Browsing by Author "Kang, Ho Young"
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Characterization of the avian GLUT1 glucose transporter: differential regulation of GLUT1 and GLUT3 in chicken embryo fibroblasts.
Wagstaff, Patricia; Kang, Ho Young; Mylott, Dawn; Robbins, Penni J.; White, Martyn K. (East Carolina University, 1995-11)Vertebrate cells that are transformed by oncogenes such as v-src or are stimulated by mitogens have increased rates of glucose uptake. In rodent cels, the mechanisms whereby glucose transport is up-regulated are well ... -
Identification and Characterization of alcR, a Gene Encoding an AraC-Like Regulator of Alcaligin Siderophore Biosynthesis and Transport in Bordetella pertussis and Bordetella bronchiseptica
Beaumont, Fiona C.; Kang, Ho Young; Brickman, Timothy J.; Armstrong, Sandra K. (East Carolina University, 1998-02)A Bordetella bronchiseptica iron transport mutant was isolated following an enrichment procedure based on streptonigrin resistance. The mutant displayed a growth defect on iron-restricted medium containing ferric alcaligin ... -
Identification and characterization of iron-regulated Bordetella pertussis alcaligin siderophore biosynthesis genes.
Kang, Ho Young; Brickman, Timothy J.; Beaumont, Fiona C.; Armstrong, Sandra K. (East Carolina University, 1996-08)Bordetella bronchiseptica mutants BRM1, BRM6, and BRM9 fail to produce the native dihydroxamate siderophore alcaligin. A 4.5-kb BamHI-SmaI Bordetella pertussis genomic DNA fragment carried multiple genes required to restore ... -
Transcriptional Activation of Bordetella Alcaligin Siderophore Genes Requires the AlcR Regulator with Alcaligin as Inducer
Brickman, Timothy J.; Kang, Ho Young; Armstrong, Sandra K. (East Carolina University, 2001-01)Genetic and biochemical studies have established that Fur and iron mediate repression of Bordetella alcaligin siderophore system (alc) genes under iron-replete nutritional growth conditions. In this study, transcriptional ... -
Transcriptional Analysis of the Bordetella Alcaligin Siderophore Biosynthesis Operon
Kang, Ho Young; Armstrong, Sandra K. (East Carolina University, 1998-02)The alc gene cluster of Bordetella pertussis includes three genes, alcA, alcB, and alcC, which are involved in alcaligin siderophore biosynthesis in response to iron starvation. The production of AlcA, AlcB, and AlcC in ...