Browsing by Subject "Sarcopenia"
Now showing items 1-6 of 6
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Cleaved Caspase-3 Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2011)In addition to suppressing protein synthesis and activating protein degradation in skeletal muscle and other cell types, 5'-AMP-activated protein kinase (AMPK) is known to stimulate nuclear apoptosis in non-muscle cells ... -
Does AMP-Activated Protein Kinase Negatively Mediate Aged Fast-Twitch Skeletal Muscle Mass?
(East Carolina University, 2008-10)The activity of 5'-adenosine monophosphate–activated protein kinase, a negative regulator of cell size, is up-regulated with age in resting and overloaded fast-twitch skeletal muscle but not slowtwitch muscle. Here, we ... -
Effects Of Extracellular Matrix Stiffness On Muscle Fiber Mechanotransduction Signaling In Aged Rats
(East Carolina University, 2015)The loss of muscle mass with age, termed sarcopenia, is a common problem among the over 60 years-old population. Resistance training is often prescribed as treatment, but older adults have shown a reduced response to ... -
Muscle stiffness as a cause of reduced muscle volume - a reliability study
(2014-12)A leading cause of impairment in elderly individuals is sarcopenia, the progressive deterioration of muscle size and strength, which ultimately limits muscle functionality. The loss of muscular strength is directly correlated ...