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Gene-environment interactions in sarcoidosis
(East Carolina University, 2007-05)
Susceptibility to most human diseases is polygenic, with complex interactions between functional polymorphisms of single genes governing disease incidence, phenotype, or both. In this context, the contribution of any ...
Human antibodies for immunotherapy development generated via a human B cell hybridoma technology
(East Carolina University, 2006-03-07)
Current strategies for the production of therapeutic mAbs include
the use of mammalian cell systems to recombinantly produce Abs
derived from mice bearing human Ig transgenes, humanization of
rodent Abs, or phage ...