Now showing items 1-20 of 30

  • Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes. 

    Sinha, Madhur K.; Taylor, Lucy G.; Pories, Walter J.; Flickinger, Edward G.; Meelheim, Diane; Atkinson, Samuel M.; Sehgal, Narinder S.; Caro, Jose F. (East Carolina University, 1987-10)
    We have tested the hypothesis that in vitro exposure of insulin- resistant adipocytes with insulin results in improved insulin action. A primary culture system of adipocytes from obese subjects with ...
  • Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver. 

    Caro, Jose F.; Poulos, John; Ittoop, Olivia; Pories, Walter J.; Flickinger, Edward G.; Sinha, Madhur K. (East Carolina University, 1988-04)
    Insulin-like growth factor-I (IGF-I) in human hepatoma cells (HEP-G2) has, in addition to its effect on cell growth, shortterm metabolic effects acting through its own receptor. We have demonstrated that normal ...
  • Thoracic neuroblastoma presenting as a cystic hygroma. 

    Ganick, D. J.; Kodroff, M. B.; Marrow, H. G.; Holbrook, C. T.; Pories, Walter J. (East Carolina University, 1988-10)
    A case of thoracic neuroblastoma with extension into the supraclavicular fossa is described. By physical examination and ultrasound the patient was thought to have a cystic hygroma with mediastinal extension. A 'cystic' ...
  • Transplantation and the Trauma Surgeon 

    Cunningham, Paul R. G.; Foil, M. Beth (East Carolina University, 1990-11)
    The number of satisfactory vascular organs suitable for organ transplantation can be increased appreciably by a close working relationship between traumatologists and transplant surgeons. Benefits will derive from more ...
  • Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. 

    Friedman, Jacob E.; Dohm, G. Lynis; Leggett-Frazier, Nancy; Elton, Charles W.; Tapscott, Edward B.; Pories, Walter P.; Caro, Jose F. (East Carolina University, 1992-02)
    A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal ...
  • Is type II diabetes mellitus (NIDDM) a surgical disease? 

    Pories, Walter J.; MacDonald, Kenneth G. Jr.; Flickinger, Edward G.; Dohm, G. Lynis; Sinha, Madhur K.; Barakat, Hisham A.; May, Harold J.; Khazanie, Prabhaker; Swanson, Melvin S.; Morgan, Elizabeth; Leggett-Frazier, Nancy; Long, Stuart D.; Brown, Brenda M.; O'Brien, Kevin; Caro, Jose F. (East Carolina University, 1992-06)
    Since February 1, 1980, 515 morbidly obese patients have undergone the Greenville gastric bypass (GGB) operation. Of these, 212 (41.2%) were euglycemic, 288 (55.9%) were either diabetic or had glucose intolerance, and ...
  • Civilian field surgery in the rural trauma setting: a proposal for providing optimal care. 

    Foil, M. Beth; Cunningham, Paul R. G.; Hale, John C.; Benson, Nicholas H.; Treurniet, Starr (East Carolina University, 1992-09)
    Rural trauma presents unique problems for surgical care. While military surgeons are prepared to provide care at or near the scene of battle, civilian literature is devoid of reports for care provided by surgeons at sites ...
  • Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor. 

    Burguera, Bartolome; Elton, Charles W.; Tapscott, Edward B.; Pories, Walter J.; Dimarchi, Richard; Sakano, Katsu-ichi; Dohm, G. Lynis (East Carolina University, 1994-06-15)
    Although the growth-promoting effects of insulin-like growth factor II (IGF-II) have been intensively studied, the acute actions of this hormone on glucose metabolism have been less well evaluated, especially in skeletal ...
  • Gastrogastric fistulas. A complication of divided gastric bypass surgery. 

    Cucchi, Sharon G. D.; Pories, Walter J.; MacDonald, Kenneth G.; Morgan, Elizabeth J. (East Carolina University, 1995-04)
    Objective This report warns that gastrogastric fistulas may follow the division of the stomach in bariatric surgery. Summary Background Data Although surgery is the most effective therapy for morbid obesity, the ...
  • The Ripped Cava 

    Cunningham, Paul R. G.; Foil, M. Beth (East Carolina University, 1995-04)
    Lacerations of the inferior vena cava are associated with a high mortality and may be difficult to repair. The majority of injuries are due to penetrating trauma. Rapid transportation to definitive surgical care with ...
  • Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. 

    Pories, Walter J.; Swanson, Melvin S.; MacDonald, Kenneth G.; Long, Stuart B.; Morris, Patricia G.; Brown, Brenda M.; Barakat, Hisham A.; deRamon, Richard A.; Israel, R. Gay; Dolezal, Jeanette M.; Dohm, G. Lynis (East Carolina University, 1995-09)
    OBJECTIVE: This report documents that the gastric bypass operation provides long-term control for obesity and diabetes. SUMMARY BACKGROUND DATA: Obesity and diabetes, both notoriously resistant to medical therapy, continue ...
  • Multicenter Trial of Sentinel Node Biopsy for Breast Cancer Using Both Technetium Sulfur Colloid and Isosulfan Blue Dye 

    Tafra, Lorraine; Lannin, Donald R.; Swanson, Melvin S.; Van Eyk, Jason J.; Verbanac, Kathryn M.; Chua, Arlene N.; Ng, Peter C.; Edwards, Maxine S.; Halliday, Bradford E.; Henry, C. Alan; Sommers, Linda M.; Carman, Claire M.; Molin, Melinda R.; Yurko, John E.; Perry, Roger R.; Williams, Robert (East Carolina University, 2001-01)
    Objective To determine the factors associated with false-negative results on sentinel node biopsy and sentinel node localization (identification rate) in patients with breast cancer enrolled in a multicenter ...
  • Robotic Surgical Training in an Academic Institution 

    Chitwood, W. Randolph; Nifong, L. Wiley; Chapman, William H. H.; Felger, Jason E.; Bailey, B. Marcus; Ballint, Tara; Mendleson, Kim G.; Kim, Victor B.; Young, James A.; Albrecht, Robert A. (East Carolina University, 2001-10)
    Objective To detail robotic procedure development and clinical applications for mitral valve, biliary, and gastric reflux operations, and to implement a multispecialty robotic surgery training curriculum for both ...
  • Brachial plexopathy after prone positioning 

    Goettler, Claudia E.; Pryor, John P.; Reilly, Patrick M. (East Carolina University, 2002-12)
    Two cases of brachial plexus injury after prone position in the intensive care unit are described. Mechanisms of brachial plexus injury are described, as are methods for prevention of this unusual complication. Originally ...
  • Post treatment protector device 

    Grady, Shelia; Staubes, Laura; Lalikos, Janice (2003-12-09)
  • Diabetes: The Evolution of a New Paradigm 

    Pories, Walter J. (East Carolina University, 2004-01)
  • Identification and Characterization of Optimal Gene Expression Markers for Detection of Breast Cancer Metastasis 

    Backus, John; Laughlin, Todd; Wang, Yixin; Belly, Robert; White, Robert; Baden, Jon; Min, C. Justus; Mannie, Ann; Tafra, Lorraine; Atkins, David; verbanac, Kathryn M. (East Carolina University, 2005-08)
    Sentinel lymph node (SLN) status is highly predictive of overall axillary lymph node involvement in breast cancer. Historically, SLN-positive patients have undergone axillary lymph node dissection in a second ...
  • Physical Activity Levels of Patients Undergoing Bariatric Surgery in the Longitudinal Assessment of Bariatric Surgery (LABS) Study 

    King, W. C.; Belle, S. H.; Eid, G. M.; Dakin, G. F.; Inabnet, W. B.; Mitchell, J. E.; Patterson, E. J.; Courcoulas, A. P.; Flum, D. R.; Chapman, William H. H.; Wolfe, B. M. (East Carolina University, 2008)
    Background- Bariatric surgery candidates' physical activity (PA) level may contribute to the variability of weight loss and body composition changes following bariatric surgery. However, there is little research describing ...
  • Bariatric Surgery: Risks and Rewards 

    Pories, Walter J. (East Carolina University, 2008-11)
    Context: Over 23 million Americans are afflicted with severe obesity, i.e. their body mass index (in kilograms per square meter) values exceed 35. Of even greater concern is the association of the adiposity with comorbidities ...
  • Perforated gastric corpus in a strangulated paraesophageal hernia: a case report 

    Shafii, Alexis E.; Agle, Steven C.; Zervos, Emmanuel E. (East Carolina University, 2009-05-07)
    Introduction: Patients with paraesophageal hernias often present secondary to chronic symptomatology. Infrequently, acute intestinal ischemia and perforation can occur as a consequence of paraesophageal hernias with ...