Browsing Dissertations by Title
Now showing items 597-616 of 1044
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Mechanistic Strategies of Two-component Flavin-dependent Monooxygenases Involved in Sulfur Acquisition
(East Carolina University, 2023-08-09)All organisms require sulfur for diverse metabolic and physiological processes. Unlike mammals, bacteria are often deprived of sulfur in their natural habitat. To meet their sulfur needs, bacteria express various proteins ... -
Medical Family Therapy : Conceptual Clarification and Consensus for an Emerging Profession
(East Carolina University, 2010)The term Medical Family Therapy (MedFT) was coined in the early 1990s (McDaniel, Hepworth, & Doherty, 1992a) by a team of family therapists and a family psychologist. Since then there has been growing interest in MedFT, ... -
MEDICAL FAMILY THERAPY IN A PRIMARY CARE SETTING : A MODEL OF INTEGRATION
(East Carolina University, 2011)As the profession of marriage and family therapy (MFT), as well as the emerging sub-discipline of medical family therapy (MedFT), continue to grow and evolve within the current mental health care system, the arena of primary ... -
Medical Family Therapy Meets Childhood Obesity
(East Carolina University, 2010)The dissertation is a compilation of two journal articles. The first article is a literature review that addresses integrated care for childhood obesity with consideration for clinical, operational, and financial practices. ... -
MEDICAL PROVIDERS' VIEWS OF MEDICALLY UNEXPLAINED ILLNESS AND MEDICALLY UNEXPLAINED SYMPTOMS
(East Carolina University, 2013)Patients who present with medically unexplained illnesses or medically unexplained symptoms (MUI/S) tend to be higher utilizers of healthcare services and have significantly greater healthcare costs than other patients, ... -
Memetic Rhetorical Theory in Technical Communication: Re-Constructing Ethos in the Post-Fact Era
(East Carolina University, 2018-07-20)This dissertation interrogates existing interpretations of ethos by analyzing the spread of misinformation through online communities. In particular, this dissertation argues that the rhetorical concept of ethos should ... -
Mental Health Professionals' Attitudes toward Clients with Antisocial Personality Disorder
(East Carolina University, 2017-04-19)Clients with personality disorder are treated throughout the United States' healthcare system. Research suggests that mental health professionals' attitudes' toward clients with personality disorders are poor. However, ... -
A META-ANALYSIS OF RESEARCH ON THE MEDIATED EFFECTS OF PRINCIPAL LEADERSHIP ON STUDENT ACHIEVEMENT : EXAMINING THE EFFECT SIZE OF SCHOOL CULTURE ON STUDENT ACHIEVEMENT AS AN INDICATOR OF TEACHER EFFECTIVENESS
(East Carolina University, 2009)The leadership of the school principal has long been associated with teacher effectiveness and student achievement. Research on the topic of principal leadership supports this association (Hallinger, Bickman, & Davis, 1996; ... -
Metabolic Inflexibility in Response to Lipid Oversupply with Obesity: Epigenetic Modifications Play a Role
(East Carolina University, 2013)The ability to adjust substrate oxidation according to nutrient availability has been termed `metabolic flexibility' and is a critical factor in overall metabolic health. In respect to fatty acid oxidation (FAO) metabolic ... -
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ... -
METHODS OF IDENTIFYING NEUROLOGICAL DELIRIUM (MIND) STUDY
(East Carolina University, 8/5/2020)Delirium is a major concern for critically ill older patients because it is associated with significant risk to quality of life and mortality. The United States spends approximately $164 billion in Medicare funding annually ... -
Microbial community response to environmental change during the Anthropocene
(East Carolina University, 2021-05-03)Microbial community composition and functional potential can be affected by human-derived environmental changes during the Anthropocene with important consequences for elemental cycling and whole ecosystem processes. This ... -
Microglial dysfunction as an early susceptibility to Alzheimer's disease: the exacerbating role of developmental toxicity
(East Carolina University, 2017-07-25)The association between perturbations to neuroimmune development and susceptibility to adult neurodegenerative diseases, like Alzheimer's disease (AD), may undersore a putative pathogenic role for gradual microglial ... -
MICRONOME AND KSHV INFECTION: IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF CELLULAR MICRORNAS DURING VIRUS ENTRY
(East Carolina University, 2018-04-17)Kaposi's sarcoma-associated herpesvirus (KSHV), is the most recently identified human herpesvirus and causes a variety of human malignancies. KSHV is etiologically associated with Kaposi's sarcoma (KS), primary effusion ... -
MINORITY STRESS, RISKY BEHAVIORS, AND SEXUAL SCRIPTING AMONG TRANSGENDER COLLEGE STUDENTS: A MIXED METHODS STUDY
(East Carolina University, 2019-07-11)Despite more transgender and gender nonconforming students entering college, little is known about their minority stress and resilience experiences or about how minority stress and resilience factors influence their sexual ... -
Mobile Assessment of the Dynamic Relationships between Experiential Avoidance, Mood, Stress, and Adherence in Cardiopulmonary Rehabilitation
(East Carolina University, 2020-06-22)Background: Despite the well-documented benefits of attending cardiopulmonary rehabilitation (CVPR) for many patients following acute cardiac or pulmonary events, adherence and completion rates remain suboptimal. Increased ... -
Modern and Classic Quantum Chemistry: Modeling Rhodium-Catalyzed Hydroacylation with Advanced Tools and the Development and Application of Software to Examine Simple Bonding Interactions in a Basis of Molecular Fragments
(East Carolina University, 8/5/2020)In this dissertation, both modern and classic computational methods are utilized to examine two problems of interest in the field of chemistry. The first problem involves a complex rhodium-catalyzed hydroacylation reaction ... -
MODIFICATION OF CELL SURVIVAL RATES BY CERIUM OXIDE NANOPARTICLES FOR EXPOSURE TO PROTON RADIATION
(East Carolina University, 2017-05-03)Radiation therapy is a well-established and widely used treatment for a variety of malignancies in the human body. Current radiotherapy methods most frequently use x-rays to deliver a lethal dose to tumors with sufficient ... -
MODULATING MMP-9 SUBSTRATE PREFERENCE TO REDUCE INFLAMMATION POST-MI
(East Carolina University, 2023-12-08)Worldwide, the prevalence of cardiovascular disease (CVD) is escalating, with myocardial infarction (MI) significantly contributing to the heightened rates of morbidity and mortality. Notably, one in every four MI patients ... -
Modulation of experimental autoimmune myocarditis with cytokine-myosin fusion proteins and novel cardiac peptides
(2016-05-16)Infectious agents that induce cross-reactive myocarditic T cell responses may cause autoimmune inflammation of the heart, dilated cardiomyopathy (DCM), and heart failure. The purpose of this study was to evaluate the ...