Browsing Dissertations by Submit Date
Now showing items 1-20 of 64
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Augmented coronary vascular smooth muscle response to endothelin-1 exacerbates cardiac injury following pulmonary exposure to engineered nanomaterials
(East Carolina University, 2014)Multi-walled carbon nanotubes (MWCNT) and 60-carbon fullerenes (C60) are important engineered nanoparticles (ENP) used across industry. Exposure to ENP potentially promotes cardiovascular detriments. The hypotheses that ... -
The induction of antigen-specific immunological tolerance and attenuation of inflammation via cytokine antigen fusion protein therapy in a mouse model of pulmonary inflammation
(East Carolina University, 2014)Allergic asthma is a significant medical issue, affecting more than 300 million individuals and causing approximately 250,000 deaths each year. Current asthma therapies temporarily minimize discomfort and manage symptoms, ... -
LEGISLATOR SUPPORT FOR NEW PUBLIC HIGHER EDUCATION INITIATIVES : A CASE STUDY OF THE ESTABLISHMENT OF THE EAST CAROLINA UNIVERSITY SCHOOL OF DENTAL MEDICINE
(East Carolina University, 2014)This study addresses the need for leaders in public higher education to possess a general knowledge of how new initiatives in public higher education gain support from state legislators to advance and implement their ... -
New nurse transitions: a qualitative study of perceived difficulties
(East Carolina University, 2013)The transition from student to registered nurse has proven difficult for new graduate nurses. While organizations have implemented structures and processes to support new nurse transition into practice, new nurse turnover ... -
Integrated Primary Care : A Systematic Review of Study Design and Program Characteristics
(East Carolina University, 2012)Integrated primary care (IPC), the integration of medical and behavioral health professionals, is a viable part of the solution for the United States' fragmented health care delivery system. Over the past decade or so, ... -
A PRELIMINARY EXAMINATION OF THE INTENDED PURPOSE, ACTUAL USE, AND PERCEIVED BENEFIT OF DISTRICT-LED INTERIM ASSESSMENTS ON STUDENT ACHIEVEMENT IN NORTH CAROLINA SCHOOLS
(East Carolina University, 2012)This study examined the intended purposes, actual uses, and perceived benefits of interim assessments on student achievement from the perspectives of district leaders, school administrators, and classroom teachers. ... -
A PRELIMINARY EXAMINATION OF THE IMPACT OF A STRUCTURED PRINCIPAL NETWORK ON PRINCIPAL BURNOUT
(East Carolina University, 2012)This study examined the extent to which participation in a formal network has on a principal's personal perception of burnout as measured by the Maslach Burnout Inventory for Educators (MBI-E). The MBI-E consists of 22 ... -
NCAA ATHLETIC DIRECTORS' SELF-PERSPECTIVE OF TRANSFORMATIONAL/TRANSACTIONAL LEADERSHIP
(East Carolina University, 2012)The purpose of this study was to examine NCAA athletic directors' (ADs') perceptions of their own leadership styles as they relate to the five dimensions of transformational leadership and the three dimensions of transactional ... -
THE IMPACT OF STATE AND FEDERAL ACCOUNTABILITY STANDARDS UPON THE IMPLEMENTATION OF INCLUSION IN JOHNSTON COUNTY, NC HIGH SCHOOLS
(East Carolina University, 2012)As student accountability models have become the norm in the United States, first in individual states such as North Carolina and then throughout the nation with No Child Left Behind (NCLB), the implementation of inclusion ... -
THEOLOGICAL DISCUSSION AND INSTITUTIONAL CHANGE AT A CHURCH-RELATED INSTITUTION
(East Carolina University, 2012)This study explores the relationship between theological discussion and organizational change within a church-related institution. The qualitative case study examines the dialogue on a campus that received a Lilly Endowment ... -
SKELETAL MUSCLE LIPID PARTITIONING : CONSEQUENCES OF ALTERATIONS IN ACYL-COA SYNTHETASE-5 AND DIGLYCERIDE ACYLTRANFERASE-1 EXPRESSION
(East Carolina University, 2011)An oversupply of fatty acids and inadequacies in their partitioning toward oxidation and/or storage will lead to disruptions in cellular homeostasis. Reductions in mitochondrial content and lower rates of fatty acid ... -
EXPLORING THE RELATIONSHIP BETWEEN DIFFERENTIATED INSTRUCTION AND STUDENT PERFORMANCE
(East Carolina University, 2011)Differentiated instruction (DI) is a collection of strategies utilized to increase student achievement and engagement. School districts are using the strategies of differentiated instruction to increase student academic ... -
A STUDY TO DETERMINE THE CONCURRENT VALIDITY BETWEEN COURSE GRADES AND STANDARDIZED ASSESSMENT RESULTS
(East Carolina University, 2011)This study sought to determine the concurrent validity between course grades and performance on standardized test in classrooms where nonachievement factors were separated from the reporting of achievement factors in a ... -
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ... -
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
(East Carolina University, 2011)Mitochondrial respiratory capacity and oxidative stress have been implicated in the development of insulin resistance (IR) and type II diabetes. A causative role of mitochondrial oxidative stress in the etiology of ... -
Decisional Balance Among Potential ICD Recipients : Development Of The Implantable Cardioverter Defibrillator Decision Analysis Scale (ICD-DAS)
(East Carolina University, 2011)Sudden cardiac death is a well-documented public health problem resulting in 400,000 deaths in the U.S. annually. The Implantable Cardioverter Defibrillator (ICD) has demonstrated benefit in reducing mortality in at risk ... -
The Declaration of Independence : A New Genre in Political Discourse or Mixed Genres in an Unlikely Medium?
(East Carolina University, 2011)The dissertation shows how mismatched content/medium relationships can supersede the responses of traditional pairings when the medium dominates the discursive power of the discourse. The dissertation, in part, looks at a ... -
A COMPARATIVE STUDY OF THE ACADEMIC PERFORMANCE OF COMMUNITY COLLEGE TRANSFER STUDENTS AND NATIVE STUDENTS AT SELECTED STATE UNIVERSITIES IN NORTH CAROLINA
(East Carolina University, 2011)Students, who complete their first two years of higher education at community colleges, must be prepared for the rigorous coursework at four-year institutions. The purpose of this study was to provide a comprehensive update ... -
TEACHER QUALITY FACTORS MEDIATING ACHIEVEMENT IN HIGH POVERTY SCHOOLS
(East Carolina University, 2011)The impact of poverty on student achievement was thoroughly researched. Researchers have determined that poverty has a direct negative impact on student achievement. This study analyzed four aspects of teacher quality ... -
MEDICAL FAMILY THERAPY IN A PRIMARY CARE SETTING : A MODEL OF INTEGRATION
(East Carolina University, 2011)As the profession of marriage and family therapy (MFT), as well as the emerging sub-discipline of medical family therapy (MedFT), continue to grow and evolve within the current mental health care system, the arena of primary ...