Search
Now showing items 31-40 of 54
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)
The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...
Insights into the Evolution of Environmental Health
(2009-03-13)
Muscle Work Discrepancy during Incline and Decline Running at Three Speeds
(East Carolina University, 2009)
Introduction: Previous research has explored muscle function during gait and this work has shown that more positive mechanical muscle work is produced in gait tasks that primarily raise the center of mass (incline gait ...
Gender Differences in Aerobic and Work Capacity During Plantar Flexion Exercise
(East Carolina University, 2009)
Maximal oxygen consumption (VO2max) is lower in females compared to males during traditional whole body, systemic exercise. These differences in VO2max between men and women are still present even after correcting for ...
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)
A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ...
Muscles do more positive than negative work in human locomotion
(East Carolina University, 2007-10)
Muscle work during level walking and ascent and descent ramp and stairway walking was assessed in order to explore the proposition that muscles perform more positive than negative work during these locomotion tasks. Thirty ...
How do low horizontal forces produce disproportionately high torques in human locomotion?
(East Carolina University, 2008)
Although horizontal ground forces are only ~15% of vertical forces, they account for 47% and 33% of the metabolic cost in walking and running. To explain these disproportionately high metabolic costs we hypothesized that ...
Effect of Duodenal-Jejunal Bypass on Skeletal Muscle Insulin Signaling in Goto-Kakizaki Rats
(East Carolina University, 2009)
Gastric bypass surgery (RYGBP) for the treatment of obesity has proven to clinically reverse type 2 diabetes mellitus. RYGBP involves both gastric reduction and bypass of the proximal small intestine. Duodenal-Jejunal ...
Review of microdialysis in brain tumors, from concept to application: First Annual Carolyn Frye-Halloran Symposium
(East Carolina University, 2004-01)
In individuals with brain tumors, pharmacodynamic and pharmacokinetic studies of therapeutic agents have historically used analyses of drug concentrations in serum or cerebrospinal fluid, which unfortunately do not necessarily ...
Pubic Lice (Pthirus pubis): History, Biology and Treatment vs. Knowledge and Beliefs of US College Students
(East Carolina University, 2009-02)
Pubic lice (Pthirus pubis) maintain a worldwide parasitic population infesting two to over 10 percent of human populations, continuing a presence that has been constant since early evidence 10,000 years ago. Outbreaks in ...