Systematic review of diagnostic tests for vaginal trichomoniasis.
Author
Patel, Sangnya R.; Wiese, Wilhelmine; Patel, Sanjay C.; Ohl, Christopher; Byrd, James C.; Estrada, Carlos A.
Abstract
Objective: To review critically and to summarize the evidence of diagnostic tests and culture media for the diagnosis of Trichomonas vaginitis. Methods: We performed a systematic review of literature indexed in MEDLINE of studies that used Trichomonas culture as the reference standard (9,882 patients, 35 studies). Level I studies (5,047 patients, 13 studies) fulfilled at least two of three criteria: 1) onsecutive patients were evaluated prospectively, 2) decision to culture was not influenced by test results, and 3) there was independent and blind comparison to culture. Results: The sensitivity of the polymerase chain reaction technique (PCR) was 95% (95% CI 91% to 99%), and the specificity was 98% (95% CI 96% to 100%). One study was classified as Level I evidence (52 patients). The sensitivity of the enzyme-linked immunosorbent assay was 82% (95% CI 74% to 90%), and the specificity was 73% (95% CI 35% to 100%). The sensitivity of the direct
fluorescence antibody was 85% (95% CI 79% to 90%), and the specificity was 99% (95% CI 98% to 100%). Sensitivities of culture media were 95% for Diamond’s, 96% for Hollander, and 95% for
CPLM. Conclusions: The sensitivity and specificity of tests to diagnose trichomoniasis vary widely. Originally published Infectious Diseases in Obstetrics and Gynecology, Vol. 8, No. 5-6, 2000
Date
2000
Citation:
APA:
Patel, Sangnya R., & Wiese, Wilhelmine, & Patel, Sanjay C., & Ohl, Christopher, & Byrd, James C., & Estrada, Carlos A.. (January 2000).
Systematic review of diagnostic tests for vaginal trichomoniasis..
Infectious Diseases in Obstetrics and Gynecology,
8(5-6),
248-
6 p. 248-257. Retrieved from
http://hdl.handle.net/10342/3375
MLA:
Patel, Sangnya R., and Wiese, Wilhelmine, and Patel, Sanjay C., and Ohl, Christopher, and Byrd, James C., and Estrada, Carlos A..
"Systematic review of diagnostic tests for vaginal trichomoniasis.". Infectious Diseases in Obstetrics and Gynecology.
8:5-6. (248-257),
January 2000.
March 18, 2024.
http://hdl.handle.net/10342/3375.
Chicago:
Patel, Sangnya R. and Wiese, Wilhelmine and Patel, Sanjay C. and Ohl, Christopher and Byrd, James C. and Estrada, Carlos A.,
"Systematic review of diagnostic tests for vaginal trichomoniasis.," Infectious Diseases in Obstetrics and Gynecology 8, no.
5-6 (January 2000),
http://hdl.handle.net/10342/3375 (accessed
March 18, 2024).
AMA:
Patel, Sangnya R., Wiese, Wilhelmine, Patel, Sanjay C., Ohl, Christopher, Byrd, James C., Estrada, Carlos A..
Systematic review of diagnostic tests for vaginal trichomoniasis.. Infectious Diseases in Obstetrics and Gynecology.
January 2000;
8(5-6):
248-257.
http://hdl.handle.net/10342/3375. Accessed
March 18, 2024.
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Publisher
East Carolina University