Review: Carbon Nanotubes and Chronic Granulomatous Disease
Barna, Barbara P.; Judson, Marc A.; Thomassen, Mary Jane
Use of nanomaterials in manufactured consumer products is a rapidly expanding industry and potential toxicities are just beginning to be explored. Combustion-generated multiwall carbon nanotubes (MWCNT) or nanoparticles are ubiquitous in non-manufacturing environments and detectable in vapors from diesel fuel, methane, propane, and natural gas. In experimental animal models, carbon nanotubes have been shown to induce granulomas or other inflammatory changes. Evidence suggesting potential involvement of carbon nanomaterials in human granulomatous disease, has been gathered from analyses of dusts generated in the World Trade Center disaster combined with epidemiological data showing a subsequent increase in granulomatous disease of first responders. In this review we will discuss evidence for similarities in the pathophysiology of carbon nanotube-induced pulmonary disease in experimental animals with that of the human granulomatous disease, sarcoidosis.
Barna, Barbara P., & Judson, Marc A., & Thomassen, Mary Jane. (June 2014). Review: Carbon Nanotubes and Chronic Granulomatous Disease. Nanomaterials, 4(2), 508- 521. Retrieved from http://hdl.handle.net/10342/4445
Barna, Barbara P., and Judson, Marc A., and Thomassen, Mary Jane. "Review: Carbon Nanotubes and Chronic Granulomatous Disease". Nanomaterials. 4:2. (508-521), June 2014. June 21, 2018. http://hdl.handle.net/10342/4445.
Barna, Barbara P. and Judson, Marc A. and Thomassen, Mary Jane, "Review: Carbon Nanotubes and Chronic Granulomatous Disease," Nanomaterials 4, no. 2 (June 2014), http://hdl.handle.net/10342/4445 (accessed June 21, 2018).
Barna, Barbara P., Judson, Marc A., Thomassen, Mary Jane. Review: Carbon Nanotubes and Chronic Granulomatous Disease. Nanomaterials. June 2014; 4(2): 508-521. http://hdl.handle.net/10342/4445. Accessed June 21, 2018.