Author | Read, Marjorie S. | |
Author | Reddick, Robert L. | |
Author | Bode, Arthur P. | |
Date Accessioned | 2016-02-10T17:52:02Z | |
Date Available | 2016-02-10T17:52:02Z | |
Date of Issue | 1999-11-30 | |
Identifier (Other) | U.S. Patent No. 5,994,315 | |
Identifier (URI) | http://hdl.handle.net/10342/5203 | |
Description | Fixed-dried human blood platelets and processes for preparing the same are disclosed. The platelets, upon reconstitution; adhere to thrombogenic surfaces; do not adhere to non-thrombogenic surfaces; undergo shape change (spreading) upon adhering to a thrombogenic surface; adhere to one another to form a hemostatic plug upon adhering to a thrombogenic surface; and release their granular contents. Pharmaceutical formulations containing the same are also disclosed. The platelets are preferably fixed by means of a fixative such as formaldehyde, paraformaldehyde, or glutaraldehyde, or fixed by means of a permanganate fixate. The platelets are preferably dried by lyophilization. | en_US |
Title | Pharmaceutically acceptable fixed-dried human blood platelets | en_US |
Type | Patent | en_US |