Browsing Microbiology and Immunology by Author "Alameen, Ayman A.M."
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The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells
Simioni, Carolina; Cani, Alice; Martelli, Alberto M.; Zauli, Giorgio; Alameen, Ayman A.M.; Ultimo, Simona; Tabellini, Giovanna; McCubrey, James A.; Capitani, Silvano; Neri, Luca M. (2015-07)Hepatocellular carcinoma (HCC) is one of the most common lethal human malignancies worldwide and its advanced status is frequently resistant to conventional chemotherapeutic agents and radiation. We evaluated the cytotoxic ...