Browsing Microbiology and Immunology by Submit Date
Now showing items 1-20 of 268
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STRUCTURE-FUNCTION ANALYSIS OF A FAMILY OF BORRELIAL C1r INHIBITORS FROM LYME DISEASE AND RELAPSING FEVER SPIROCHETES
(East Carolina University, 2023-06-01)The complement system is an ancient part of the innate immune system consisting of fluid-phase proteins that contribute to inflammation, homeostasis, and pathogen clearance. A group of vector-borne spirochetal pathogens ... -
FliL Ring Enhances the Function of Periplasmic Flagella
(2022-03-07) -
TLR-4 agonism induces CD25+ MHCIIhigh dendritic cells in association with tolerogenic antigen recognition
(East Carolina University, 2022-12-06)Autoimmune disease is a result of the breakdown in immunological self-tolerance leading to destruction of self-tissues mediated by the aberrant immune attack. In Multiple Sclerosis (MS), CD4+ T cells mediate destruction ... -
A Wzx-Wzy-like Polysaccharide Biosynthetic Pathway Contributes to Virulence in Brucella abortus 2308 through an Unknown Mechanism
(East Carolina University, 2022-08-05)Brucella abortus is an intracellular pathogen that causes spontaneous abortion in cattle and undulant fever in humans. As a member of the a-proteobacteria, B. abortus is closely related to the bacterial species Caulobacter ...