Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective
Kalogerinis, Peter T.; Poulos, John E.; Morfesis, Andrew; Daniels, Anthony; Georgakila, Stavroula; Daignualt, Thomas; Georgakilas, Alexandros G.
Background There is very small occurrence of adenocarcinoma in the small bowel. We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the molecular biology behind small bowel neoplasms and treatment options. Case The patient had a history of iron deficiency anemia and occult bleeding with extensive workup consisting of upper endoscopy, colonoscopy, capsule endoscopy, upper gastrointestinal series with small bowel follow through and push enteroscopy. Due to persistent abdominal pain and iron deficiency anemia the patient underwent push enteroscopy which revealed adenocarcinoma of the duodenum. The patient underwent en-bloc duodenectomy which revealed T3N1M0 adenocarcinoma of the 4th portion of the duodenum. Conclusions Primary duodenal carcinoma, although rare should be considered in the differential diagnosis of occult gastrointestinal bleeding when evaluation of the lower and upper GI tract is unremarkable. We discuss the current evaluation and management of this small bowel neoplasm.
Kalogerinis, Peter T., & Poulos, John E., & Morfesis, Andrew, & Daniels, Anthony, & Georgakila, Stavroula, & Daignualt, Thomas, & Georgakilas, Alexandros G.. (January 2010). Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective. BMC Gastroenterology, 10(), 109- 109. Retrieved from http://hdl.handle.net/10342/5510
Kalogerinis, Peter T., and Poulos, John E., and Morfesis, Andrew, and Daniels, Anthony, and Georgakila, Stavroula, and Daignualt, Thomas, and Georgakilas, Alexandros G.. "Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective". BMC Gastroenterology. 10:. (109-109), January 2010. April 23, 2019. http://hdl.handle.net/10342/5510.
Kalogerinis, Peter T. and Poulos, John E. and Morfesis, Andrew and Daniels, Anthony and Georgakila, Stavroula and Daignualt, Thomas and Georgakilas, Alexandros G., "Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective," BMC Gastroenterology 10, no. (January 2010), http://hdl.handle.net/10342/5510 (accessed April 23, 2019).
Kalogerinis, Peter T., Poulos, John E., Morfesis, Andrew, Daniels, Anthony, Georgakila, Stavroula, Daignualt, Thomas, Georgakilas, Alexandros G.. Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective. BMC Gastroenterology. January 2010; 10(): 109-109. http://hdl.handle.net/10342/5510. Accessed April 23, 2019.