Browsing Biology by Title
Now showing items 67-86 of 175
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Ecological effects of rising sea level on shorezone
(East Carolina University, 2009)This study examines the ecological effects of sea-level rise on shorezone in the Neuse River estuary and western Pamlico Sound, NC. Shorezone is defined here in an ecohydrological context as the area of wetland that extends ... -
Educational engagement and the environment: Investigating service learning in the nonhuman sciences
(2014)Classic definitions outline service learning as engaging students in experiential education where learning goals are reached when service activities are combined with reflective assignments. In an effort to integrate ... -
THE EFFECT OF CHANGES IN SODIUM CONCENTRATIONS ON MITOCHONDRIA
(2015-05-01)Atherosclerosis, hardening of the arteries, is the major cause of stroke, peripheral artery disease and heart attack. . Overproduction of superoxide anions in mitochondria can give rise to atherosclerosis. Superoxide anions ... -
Effect of green tea Polyphenon 60 on microRNA expression in MCF-7 breast cancer cells
(East Carolina University, 2010)In Western countries, breast cancer is the most common form of cancer and it is the second leading cause of female cancer death in America. The biochemical basis of the observed anti-oncogenic properties of green tea has ... -
Effect of MicroRNA-34c on Regenerative Axon Growth in Dorsal Root Ganglion Neurons of the Peripheral Nervous System
(East Carolina University, 2011)The peripheral nervous system is unique in its ability to regenerate axons after injury. Our lab previously assessed the miRNA expression levels of the regenerating sciatic nerve which indicated miR-34c up-regulation. ... -
Effect of Versican G1 Domain Overexpression on Hyaluronan, Hyaluronidase-2, and Synovial Joint Formation in the Embryonic Chick
(East Carolina University, 2013)Versican, an extracellular chondroitin sulfate proteoglycan which binds hyaluronan, has been hypothesized to play a role in synovial joint formation in the chick embryo. Several studies have shown versican to be involved ... -
Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
(East Carolina University, 2010)Breast cancer is one of the leading causes of deaths in women worldwide. 5-flourouracil (5-FU) is a classic chemotherapeutic drug that has been widely used in the treatment of breast cancer patients. In this study, using ... -
EFFECTS OF A REVERSE OSMOSIS-WATER TREATMENT PLANT BRINY CONCENTRATE DISCHARGED INTO AN ESTUARY.
(East Carolina University, 2010)Reverse Osmosis Water Treatment Plants (RO-WTPs) create potable water and a briny concentrate that must be disposed; often it is discharged into nearby surface waters. Currently, there is no published research to examine ... -
The Effects of Crude Oil and Chemical Dispersant Exposure on Danio rerio (zebrafish) Embryonic Development
(East Carolina University, 2014)Crude oil has been shown to cause defects in cardiovascular development in a variety of teleost species. We used the zebrafish, Danio rerio as a model to test the effects of oil and dispersant on cardiac development and ... -
The effects of environmental nickel toxicity upon survival, growth, reproduction, fecundity, and lifespan of nematodes Caenorhabditis elegans, Pristionchus pacificus, and Caenorhabditis briggsae
(East Carolina University, 2012)Nickel (II) is a common component of many natural products and man-made devices. Due to its frequent use in everyday life, relatively large amounts of nickel are being released into the environment. Nickel, however, is a ... -
The Effects of Gastrin and Hox-A1 on HT-29 Cell Proliferation
(East Carolina University, 2013)Gastrin is a gastrointestinal peptide hormone synthesized in G cells and secreted in the antrum of the stomach. Though its primary role is to stimulate the secretion of gastric acid by parietal cells, it is also involved ... -
Effects of Land Use Change on Juvenile Fishes, Blue Crab, and Brown Shrimp Abundance in the Estuarine Nursery Habitats of North Carolina
(East Carolina University, 2011)The U.S. coastal region is home to more than half of the American population. Also, the coastal counties' population is growing much faster than that of inland counties. With a high density and an increasing population, ... -
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ... -
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ... -
The effects of sodium butyrate on Hox gene expression in a human colorectal adenocarcinoma cell line, HT29.
(East Carolina University, 2013)Hox genes are a subgroup of the large family of homeobox containing genes, known to pattern anterior/posterior and proximal/distal axes during embryonic development. More recently Hox gene research has focused on the role ... -
Elucidating Gene Function with the use of Genome Wide Association Study (GWAS)
(East Carolina University, 2015)DNA replication and cell proliferation are intensely studied subjects. There have been countless experiments and hours put into better understanding how DNA is replicated and compacted, and how cells are able to proliferate ... -
Enzymatic determination of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid.
(East Carolina University, 1993-07)A specific enzymatic method to determine the amounts of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid (2,3-DHBA) was devised. A sample was incubated first with hippurate hydrolase andthenwith ... -
Epigenetic Effect of Modified Diet and Exercise on Drosophila Metabolic Phenotype and Cardiovascular Health
(2015-04)Obesity is a growing world-wide epidemic. Overweight populations are prone to a variety of morbid conditions including diabetes type 2, cardiovascular diseases, and cancers. The catastrophic increase in obesity rates, which ... -
ESTABLISHING LINKAGE BETWEEN GINS COMPLEX SUB-UNIT Sld5 AND CHECKPOINT PROTEIN Chk2 (loki) USING DROSOPHILA MELANOGASTER AS MODEL ORGANISM
(East Carolina University, 2012)Eukaryotic DNA replication is controlled by a number of proteins that ensures the process takes place accurately. GINS, a hetero-tetrameric protein complex is known to be essential for the initiation and progression of ... -
Evaluating Spatial and Temporal Overlap Between Larval Alosines and Potential Zooplankton Prey in Lower Roanoke River and Albemarle Sound, North Carolina
(East Carolina University, 2011)Spatial and temporal overlap between zooplankton and larval American shad (Alosa sapidissima), river herring (alewife A. pseudoharengus and blueback herring A. aestivalis), and hickory shad (A. mediocris) was evaluated in ...