Browsing Biology by Type"Article"
Now showing items 1-20 of 33
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Alteration of In Vivo Cellulose Ribbon Assembly by Carboxymethylcellulose and Other Polysaccharides
(East Carolina University, 1982)In vivo cellulose ribbon assembly by the Gram-negative bacterium Acetobacter xylinum can be altered by incubation in carboxymethylcellulose (CMC), a negatively charged water-soluble cellulose derivative, and also by ... -
Analyses of domains and domain fusions in human proto-oncogenes
(East Carolina University, 2009-03-17)Background: Understanding the constituent domains of oncogenes, their origins and their fusions may shed new light about the initiation and the development of cancers. Results: We have developed a computational pipeline ... -
Ancient Genome Duplications Did Not Structure the Human Hox-Bearing Chromosomes
(East Carolina University, 2001-05)The fact that there are four homeobox (Hox) clusters in most vertebrates but only one in invertebrates is often cited as evidence for the hypothesis that two rounds of genome duplication by polyploidization occurred early ... -
The AraC-Like Transcriptional Regulator DhbR Is Required for Maximum Expression of the 2,3-Dihydroxybenzoic Acid Biosynthesis Genes in Brucella abortus 2308 in Response to Iron Deprivation
(East Carolina University, 2008-03)Phenotypic evaluation of isogenic mutants derived from Brucella abortus 2308 indicates that the AlcR homolog DhbR (2,3-dihydroxybenzoic acid [2,3-DHBA] biosynthesis regulator) modulates the expression of the genes involved ... -
Bichir HoxA Cluster Sequence Reveals Surprising Trends in Ray-Finned Fish Genomic Evolution
(East Carolina University, 2004-01)The study of Hox clusters and genes provides insights into the evolution of genomic regulation of development. Derived ray-finned fishes (Actinopterygii, Teleostei) such as zebrafish and pufferfish possess duplicated Hox ... -
Bisphenol A: vom Saal and Hughes Respond
(East Carolina University, 2006-01) -
Cadherins in maternal-foetal interactions: red queen with a green beard?
(East Carolina University, 2005-03-22)Cadherins are homophilic cell surface adhesion proteins, some of which mediate interactions between maternal and foetal tissues during mammalian pregnancy. David Haig suggested that these proteins may exhibit ‘green-beard ... -
Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
(East Carolina University, 2003-03-04)The structures of membrane receptors mediating rapid, nongenomic actions of steroids have not been identified. We describe the cloning of a cDNA from spotted seatrout ovaries encoding a protein that satisfies the following ... -
Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs
(East Carolina University, 2004-09-20)Background: Cyclin-dependent kinases (CDKs) are a large family of proteins that function in a variety of key regulatory pathways in eukaryotic cells, including control over the cell cycle and gene transcription. Among the ... -
Comparison of the exoS Gene and Protein Expression in Soil and Clinical Isolates of Pseudomonas aeruginosa
(East Carolina University, 2001-04)Exoenzyme S (ExoS) is translocated into eukaryotic cells by the type III secretory process and has been hypothesized to function in conjunction with other virulence factors in the pathogenesis of Pseudomonas aeruginosa. ... -
Concerted gene recruitment in early plant evolution
(East Carolina University, 2008-07)Background: Horizontal gene transfer occurs frequently in prokaryotes and unicellular eukaryotes. Anciently acquired genes, if retained among descendants, might significantly affect the long-term evolution of the recipient ... -
Convergent evolution of bright coloration and toxicity in frogs
(East Carolina University, 2003-10-28) -
DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis
(East Carolina University, 2010-04-15)Public concerns on phthalates distributions in the environment have been increasing since they can cause liver cancer, structural abnormalities and reduce sperm counts in male reproductive system. However, few data are ... -
Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids?
(East Carolina University, 2007-06)Background: Ancient endosymbioses are responsible for the origins of mitochondria and plastids, and they contribute to the divergence of several major eukaryotic groups. Although chlamydiae, a group of obligate intracellular ... -
Enzymatic determination of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid.
(East Carolina University, 1993-07)A specific enzymatic method to determine the amounts of itoic acid, a Bacillus subtilis siderophore, and 2,3-dihydroxybenzoic acid (2,3-DHBA) was devised. A sample was incubated first with hippurate hydrolase andthenwith ... -
The evolution of coloration and toxicity in the poison frog family (Dendrobatidae)
(East Carolina University, 2001-05-22)The poison frogs (family Dendrobatidae) are terrestrial anuran amphibians displaying a wide range of coloration and toxicity. These frogs generally have been considered to be aposematic, but relatively little ... -
The evolution of parental care and egg size: a comparative analysis in frogs
(East Carolina University, 2006-03-22)The evolution of parental care and egg size has attracted considerable attention and theoretical debate. Several different hypotheses have been proposed concerning the trajectories of parental care and egg size evolution ... -
Evolution of the RNA polymerase II C-terminal domain
(East Carolina University, 2002-04-30)In recent years a great deal of biochemical and genetic research has focused on the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II. This strongly conserved domain of tandemly ... -
An Extensive New Literature Concerning Low-Dose Effects of Bisphenol A Shows the Need for a New Risk Assessment
(East Carolina University, 2005-08)Bisphenol A (BPA) is the monomer used to manufacture polycarbonate plastic, the resin lining of cans, and other products, with global capacity in excess of 6.4 billion lb/year. Because the ester bonds in these BPA-based ... -
Footprints in the sand: independent reduction of subdigital lamellae in the Namib–Kalahari burrowing geckos
(East Carolina University, 2006-04-07)Many desert organisms exhibit convergence, and certain physical factors such as windblown sands have generated remarkably similar ecomorphs across divergent lineages. The burrowing geckos Colopus, Chondrodactylus and ...