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    Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review

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    Author
    Nassar, Noha N.; Abdel-Rahman, Abdel A.
    Abstract
    Abbreviations: A2A, adenosine subtype A2A receptor; A1, adenosine subtype A1 receptor; ABC, avidin biotin complex; ABD rat, aortic barodenervated rat; α2 AR, alpha 2 adrenergic receptor; αMNE, alpha methyl norepinephrine; ATP, adenosine triphosphate; BP, blood pressure; cAMP, cyclic adenosine monophosphate; CGS21680, 2-[4-[(2-carboxyethyl)phenyl]ethylaminophenyl]ethylamino]-5′-N-ethylcarboxamidoadenosine. Selective A2A receptor agonist; CNS, central nervous system; CPA, N6-cyclopentyladenosine. Selective A1 receptor agonist; DAG, diacylglycerol; DPCPX, 8-cyclopentyl-1,3-dipropylxanthine. Selective A1 receptor antagonist; I1, imidazoline subtype 1 receptor; I.C., intracisternal; IP3, Inositol Triphosphate; I.V., intravenous; JNK, C-Jun N-terminal kinase; L-NAME, Nω-nitro-l-arginine methyl ester hydrochloride. Non-selective nitric oxide synthase inhibitor; NOS, nitric oxide synthase; NO, nitric oxide; NTS, nucleus tractus solitarius; PC-PLC, phosphatidyl choline-selective phospholipase C; PC12 cells, pheochromocytoma cells; PD98059, selective extracellular signal regulated kinase inhibitor; ERK1/2, extracellular signal regulated kinase; PDE, phosphodiesterase; PKA, protein kinase A; RVLM, rostral ventrolateral medulla; SAPK, stress activated protein kinase; SCH58261, 5-amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-∈]-1,2,4-triazolo[1,5-c]pyrimidine. Selective adenosine A2A antagonist; SHR, spontaneously hypertensive rat; SND, sympathetic neuronal discharge; SO, sham operated = conscious normotensive rats; 8-SPT, 8-(p-sulfophenyl)-theophylline. Non-selective adenosine receptor blocker; WKY, Wistar Kyoto rat
    URI
    http://hdl.handle.net/10342/5757
    Subject
     Imidazoline I1-receptor; Centrally mediated hypotension; Clonidine; Central adenosine receptors; Conscious rats; MAPK-NOS signaling 
    Date
    2014-12
    Citation:
    APA:
    Nassar, Noha N., & Abdel-Rahman, Abdel A.. (December 2014). Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review. Journal of Advanced Research, 6(3), 331- 340. Retrieved from http://hdl.handle.net/10342/5757

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Nassar, Noha N., and Abdel-Rahman, Abdel A.. "Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review". Journal of Advanced Research. 6:3. (331-340), December 2014. February 15, 2019. http://hdl.handle.net/10342/5757.
    Chicago:
    Nassar, Noha N. and Abdel-Rahman, Abdel A., "Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review," Journal of Advanced Research 6, no. 3 (December 2014), http://hdl.handle.net/10342/5757 (accessed February 15, 2019).
    AMA:
    Nassar, Noha N., Abdel-Rahman, Abdel A.. Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review. Journal of Advanced Research. December 2014; 6(3): 331-340. http://hdl.handle.net/10342/5757. Accessed February 15, 2019.
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