Browsing Physics by Issue Date
Now showing items 1-20 of 29
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Quantifying Double-Strand Breaks and Clustered Damages in DNA by Single-Molecule Laser Fluorescence Sizing
(East Carolina University, 2003-02)Fluorescence from a single DNA molecule passing through a laser beam is proportional to the size (contour length) of the molecule, and molecules of different sizes can be counted with equal efficiencies. Single-molecule ... -
The high concentration of Arg213 → Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities
(East Carolina University, 2005-01-15)The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. A mutation (Arg213→Gly; R213G) within this extracellular matrix-binding region ... -
Levels of Ca2+-Dipicolinic Acid in Individual Bacillus Spores Determined Using Microfluidic Raman Tweezers
(East Carolina University, 2007-07)Pyridine-2,6-dicarboxylic acid (dipicolinic acid [DPA]) in a 1:1 chelate with calcium ion (Ca-DPA) comprises 5 to 15% of the dry weight of spores of Bacillus species. Ca-DPA is important in spore resistance to many ... -
Role of Dipicolinic Acid in the Germination, Stability, and Viability of Spores of Bacillus subtilis
(East Carolina University, 2008-07)Spores of Bacillus subtilis spoVF strains that cannot synthesize dipicolinic acid (DPA) but take it up during sporulation were prepared in medium with various DPA concentrations, and the germination and viability of these ... -
Electron Emission from Foils and Biological Materials after Proton Impact
(East Carolina University, 2008-10)Electron emission spectra from thin metal foils with thin layers of water frozen on them (amorphous solid water) after fast proton impact have been measured and have been simulated in liquid water using the event-by-event ... -
Interaction cross sections needed for simulation of secondary electron emission spectra from thin metal foils after fast proton impact
(East Carolina University, 2009)Monte Carlo simulations of secondary electron emission from thin metal foils after fast proton impact require reliable interaction cross sections with the target under consideration. Total and energy differential inelastic ... -
Elastic and inelastic light scattering from single bacterial spores in an optical trap allows the monitoring of spore germination dynamics
(East Carolina University, 2009-05-15)Raman scattering spectroscopy and elastic light scattering intensity (ESLI) were used to simultaneously measure levels of Ca-dipicolinic acid (CaDPA) and changes in spore morphology and refractive index during germination ... -
Superdormant Spores of Bacillus Species Have Elevated Wet-Heat Resistance and Temperature Requirements for Heat Activation
(East Carolina University, 2009-09)Purified superdormant spores of Bacillus cereus, B. megaterium, and B. subtilis isolated after optimal heat activation of dormant spores and subsequent germination with inosine, D-glucose, or L-valine, respectively, germinate ... -
Development of a Diffraction Imaging Flow Cytometer for Study of Biological Cells
(East Carolina University, 2010)Visible light interacts with biological cells primarily through elastic scattering. With coherent excitation the scattered light is coherent as well and contains much information about the cells morphology but with the ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
ANALYTICAL CROSS SECTIONS FOR MOMENTUM TRANSFER TO INNER SHELL ELECTRONS
(East Carolina University, 2011)The Plane Wave Born Approximation (PWBA), the most prevalent First Born Approximation (FBA), serves as input into theories well beyond the scope of the PWBA. Using Mathematica's advanced symbolic programming capabilities ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ... -
Secondary Electron Emission Yields from Fast Fluorine Ions on Copper and Amorphous Solid Water Foils
(East Carolina University, 2011)The biological outcomes from charged particle radiation exposure are heavily influenced by the spatial patterns of energy distributed within the biological system. Monte Carlo track structure codes can be used to model ... -
COMPARATIVE ANALYSIS OF TWO HUMAN CANCER CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION
(East Carolina University, 2011)Over the past two decades, studies on the cellular response to very low dose radiation have been revolutionizing historically-held paradigms of cellular radioresponse. Indeed, a host of seemingly contradictory events have ... -
Label-free classification of cultured cells through diffraction imaging
(2011-05)Automated classification of biological cells according to their 3D morphology is highly desired in a flow cytometer setting. We have investigated this possibility experimentally and numerically using a diffraction imaging ... -
THE DESCRIPTION OF SCHUMANN ELECTROMAGNETIC RESONANCES BETWEEN EARTH AND ITS IONOSPHERE AS BOSE-EINSTEIN CONDENSATES OF EXTREMELY LOW FREQUENCY PHOTONS
(East Carolina University, 2012)The purpose of this thesis is to show that Schumann resonances between Earth and its ionosphere are Bose-Einstein condensates of extremely low frequency photons. We will show that the photon densities of the first five ... -
Analysis of Circular Dichroism and Linear Dichroism Spectroscopy
(East Carolina University, 2012)Circular Dichroism (CD) and Linear Dichroism (LD) spectroscopies measure the difference in absorption between left and right circularly polarized light and parallel and perpendicular linearly polarized light as a function ... -
In Vivo Blood Glucose Quantification Using Raman Spectroscopy
(2012)We here propose a novel Raman spectroscopy method that permits the noninvasive measurement of blood glucose concentration. To reduce the effects of the strong background signals produced by surrounding tissue and to obtain ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
Kinetics of Germination of Individual Spores of as Measured by Raman Spectroscopy and Differential Interference Contrast Microscopy
(2013)Geobacillus stearothermophilus is a gram-positive, thermophilic bacterium, spores of which are very heat resistant. Raman spectroscopy and differential interference contrast microscopy were used to monitor the kinetics of ...