Browsing Physics by Title
Now showing items 117-136 of 164
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Quantifying Double-Strand Breaks and Clustered Damages in DNA by Single-Molecule Laser Fluorescence Sizing
(East Carolina University, 2003-02)Fluorescence from a single DNA molecule passing through a laser beam is proportional to the size (contour length) of the molecule, and molecules of different sizes can be counted with equal efficiencies. Single-molecule ... -
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
(2017-09-08)Morphological changes in apoptotic cells provide essential markers for defining and detection of apoptosis as a fundamental mechanism of cell death. Among these changes, the nuclear fragmentation and condensation have ... -
RADIOSENSITIZATION OF PROSTATE CARCINOMA CELLS BY PEGYLATED METALLIC NANOPARTICLES TO PROTON IRRADIATION
(East Carolina University, 2023-05-01)One of the main goals of cancer radiation therapy is to reduce the dose to healthy tissues while maximizing the dose to malignant tissue. A special class of materials known as "radiosensitizers" has emerged that can help ... -
Realistic optical cell modeling and diffraction imaging simulation for study of optical and morphological parameters of nucleus
(2016-01)Coherent light scattering presents complex spatial patterns that depend on morphological and molecular features of biological cells. We present a numerical approach to establish realistic optical cell models for generating ... -
Resolving power of diffraction imaging with an objective: a numerical study
(2017-05)Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ... -
Role of Blood Cytokine Levels and Adiposity in Myocardial Infarction Recurrence
(2018-05)Risk factors for myocardial infarction (MI) are important as cardiovascular disease is the leading cause of death. In fact, approximately one third of adults having an MI will have another in six years. The purpose of this ... -
Role of Dipicolinic Acid in the Germination, Stability, and Viability of Spores of Bacillus subtilis
(East Carolina University, 2008-07)Spores of Bacillus subtilis spoVF strains that cannot synthesize dipicolinic acid (DPA) but take it up during sporulation were prepared in medium with various DPA concentrations, and the germination and viability of these ... -
SAFE HAVENS AND HOT SPOTS: IONIZING RADIATION IN MARTIAN PERMAFROST AND ITS INFLUENCE ON THE SURVIVAL OF ANCIENT LIFE
(East Carolina University, 2022-06-20)Permafrost on Mars is considered a primary target for the search for life. On a microscopic scale permafrost is highly non-uniform and the effective radiation dose absorbed by a microbe, and thus its survival probability, ... -
SAFE HAVENS AND HOT SPOTS: IONIZING RADIATION IN MARTIAN PERMAFROST AND ITS INFLUENCE ON THE SURVIVAL OF ANCIENT LIFE
(East Carolina University, 2022-06-20)Permafrost on Mars is considered a primary target for the search for life. On a microscopic scale permafrost is highly non-uniform and the effective radiation dose absorbed by a microbe, and thus its survival probability, ...