Browsing Health Sciences Campus by Type"Doctoral Dissertation"
Now showing items 21-40 of 298
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Anatomical and Physiological Changes Following Primary Palatoplasty Using the Buccal Flap Approach
(East Carolina University, 2021-04-14)Individuals born with cleft palate typically undergo primary palatoplasty between 6-12 months of age to repair their palate. Traditional primary palatoplasty surgical techniques include the V-Y pushback, the intravelar ... -
Antigen-specific tolerogenic vaccines inhibit autoimmune disease in a rodent model of multiple sclerosis
(East Carolina University, 2010)Multiple sclerosis (MS) is considered to be a T cell-mediated autoimmune disease directed against myelinated nerves within the central nervous system. Current therapies available to MS patients have low efficacy and are ... -
Apigenin prevents chemically-induced skin tumor formation and inhibits COX-2 expression and activity in SKH-1 mouse epidermis
(East Carolina University, 2012)The most common type of cancer in the United States is non-melanoma skin cancer (NMSC), with an estimated two million new cases diagnosed each year. Numerous malignancies including NMSC, colon, breast, and prostate cancer ... -
Appraisal of uncertainty while waiting for a kidney transplant
(East Carolina University, 2012)This study tested a middle range nursing theory to better understand the experience of uncertainty in deceased-donor kidney transplant candidates with a goal of identifying ways to improve the care of persons by nurses as ... -
Auditory and visual sustained attention on tasks with varied motivation and cognitive loads in children with and without ADHD.
(East Carolina University, 2015)Attention Deficit Hyperactivity Disorder (ADHD) is a common condition that can make tasks difficult for the children affected, particularly in a school environment. Continuous performance tasks are one means of evaluating ... -
Auditory brainstem responses to air- and bone-conducted chirp stimuli in newborns and young adults.
(East Carolina University, 2015)Over the past half a century, considerable effort has been dedicated to the development of universal newborn hearing screening (UNHS) programs across the United States. Newborn hearing screenings have progressed from ... -
Auditory event-related potentials recorded during passive listening and speech production
(East Carolina University, 2010)What is the role of audition in the process of speech production and speech perception? Specifically, how are speech production and speech perception integrated to facilitate forward flowing speech and communication? ... -
Augmented coronary vascular smooth muscle response to endothelin-1 exacerbates cardiac injury following pulmonary exposure to engineered nanomaterials
(East Carolina University, 2014)Multi-walled carbon nanotubes (MWCNT) and 60-carbon fullerenes (C60) are important engineered nanoparticles (ENP) used across industry. Exposure to ENP potentially promotes cardiovascular detriments. The hypotheses that ... -
Beyond Men's Experiences: Developing a Psychometric Scale to Measure Perceptions of Men's Fitness for Professional Nursing
(East Carolina University, 2022-04-28)Background: According to the 2021 United States (U.S) Bureau of Labor Statistics, men represent only 13% of Registered Nurses in the U. S. This minority portion of the workforce has been extensively explored through ... -
The bhuTUV and bhuO genes play vital roles in the ability of Brucella abortus to use heme as an iron source and are regulated in an iron-responsive manner by RirA and Irr
(East Carolina University, 2012)Brucella abortus is a Gram negative intracellular pathogen that causes the zoonotic disease brucellosis. Antibiotic treatment for brucellosis in humans is prolonged and sometimes followed by relapses. Currently, the United ... -
Binaural Interference in Normal Hearing Children
(East Carolina University, 2009)This study was conducted to determine if the phenomenon of binaural interference occurs in normal hearing children. To investigate the possible presence of binaural interference, comparisons of the participants' right, ... -
The Biochemical Characterization Of Neuronal K+ Channel N-Glycans And Their Role In Regulating K+ Channel Function
(East Carolina University, 2009)The Kv3 and Kv1 subfamilies of voltage–gated K+ channels are critical components which contribute to action potential repolarization throughout the central nervous system. Here, it was shown that both absolutely conserved ... -
Biopsychosocial Barriers, Motivational Interviewing, and Antiretroviral Medication Adherence in Persons Living with HIV and AIDS
(East Carolina University, 2018-04-23)Since the development of antiretroviral medications in the mid-1990s, treatment of human immunodeficiency virus (HIV) infection has improved steadily and HIV is now considered a manageable chronic condition with improved ... -
Breast feeding intention and initiation among rural, low-income Native American and African American adolescent mothers in North Carolina: testing the theory of planned behavior
(East Carolina University, 2014)Abstract Infant feeding practices can greatly impact a child's life with far reaching implications based upon decisions a mother makes for her newborn. Breastfeeding is the preferred method of infant feeding because of ... -
BREASTFEEDING SELF-EFFICACY IN WOMEN USING ASSISTIVE TECHNIQUES AND DEVICES TO ADDRESS MATERNAL AND INFANT FEEDING PROBLEMS
(East Carolina University, 2021-05-03)This dissertation used the theory of planned behavior (Ajzen, 1991, 2002) and breastfeeding self-efficacy theory (Dennis, 1999) to explore relationships among breastfeeding self-efficacy and both the source and intensity ... -
The Brucella abortus alkyl hydroperoxide reductase complex (AhpCD) is the primary scavenger of endogenous hydrogen peroxide and the ahpCD operon is regulated in response to endogenous hydrogen peroxide.
(East Carolina University, 2010)Brucella abortus is a facultative intracellular pathogen that causes abortion and infertility in cattle and relapsing fever in humans. These bacteria reside and replicate inside macrophages during infection, and the ability ... -
Cardioprotective mechanisms targeting thiol redox homeostasis and mitochondrial bioenergetics
(East Carolina University, 2016-05-03)Coronary heart disease is a leading cause of death in the United States, totaled mostly by deaths associated with myocardial infarction and fatal ventricular arrhythmias. The inability to predict the occurrence of these ... -
Cardiovascular Outcomes Following Xenobiotic Pulmonary Exposures
(East Carolina University, 2017-07-06)Cardiovascular disease remains the leading cause of mortality in the developed world. Over the past decades, investigations have demonstrated that pulmonary exposure to xenobiotic particulate matter promotes and exacerbates ... -
Casual video game play as an augmentation intervention for anxiety: a controlled study
(East Carolina University, 2014)Anxiety is an innate reaction to stress, but when excessive it can develop into a clinical disorder. Traditional anxiety treatments such as pharmaceuticals in combination with psychotherapy have established efficacy in ... -
Catecholamine metabolism via monoamine oxidase (MAO) within myocardium of individuals with type 2 diabetes
(East Carolina University, 2019-04-23)The primary comorbidity and cause of mortality in type 2 diabetes is cardiovascular disease. The structural and the functional cardiac remodeling observed in patients with type 2 diabetes has been shown to be driven by a ...