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Realistic optical cell modeling and diffraction imaging simulation for study of optical and morphological parameters of nucleus
(2016-01)
Coherent light scattering presents complex spatial patterns that depend on morphological and molecular features of biological cells. We present a numerical approach to establish realistic optical cell models for generating ...
Resolving power of diffraction imaging with an objective: a numerical study
(2017-05)
Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ...
Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation
(2017-09-08)
Morphological changes in apoptotic cells provide essential markers for defining and detection
of apoptosis as a fundamental mechanism of cell death. Among these changes, the
nuclear fragmentation and condensation have ...