Now showing items 1-3 of 3

  • Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5 

    Adderley, Shaquria P.; Thuet, Kelly M.; Sridharan, Meera; Bowles, Elizabeth A.; Stephenson, Alan H.; Ellsworth, Mary L.; Sprague, Randy S. (2011)
    Background Within erythrocytes (RBCs), cAMP levels are regulated by phosphodiesterases (PDEs). Increases in cAMP and ATP release associated with activation of β-adrenergic receptors (βARs) and prostacyclin receptors ...
  • Multiple Kinase Involvement in the Regulation of Vascular Growth 

    Adderley, Shaquria P.; Joshi, Chintamani N.; Martin, Danielle N.; Mooney, Shayna; Tulis, David A. (New York: InTech Open Access Publishers, 2012-06)
    The initial discovery of protein phosphorylation as a regulatory mechanism for the control of glycogen metabolism has led to intense interest of protein phosphorylation in regulating protein function (Cohen et al., 2001). ...
  • Phosphodiesterases Regulate BAY 41-2272-Induced VASP Phosphorylation in Vascular Smooth Muscle Cells 

    Adderley, Shaquria P.; Joshi, Chintamani N.; Martin, Danielle N.; Tulis, David Anthony (2012-02)
    BAY 41-2272 (BAY), a stimulator of soluble guanylyl cyclase, increases cyclic nucleotides and inhibits proliferation of vascular smooth muscle cells (VSMCs). In this study, we elucidated mechanisms of action of BAY in its ...