Browsing Anatomy and Cell Biology by Subject "Carcinogenesis"
Now showing items 1-2 of 2
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Apigenin Prevents UVB-Induced Cyclooxygenase 2 Expression: Coupled mRNA Stabilization and Translational Inhibition
(East Carolina University, 2007-01)Cyclooxygenase 2 (COX-2) is a key enzyme in the conversion of arachidonic acid to prostaglandins, and COX-2 overexpression plays an important role in carcinogenesis. Exposure to UVB strongly increased COX-2 protein expression ... -
THE THERAPEUTIC ROLE OF RHO GTPASES IN TUMORIGENESIS AND CHEMOTHEARPY-INDUCED PERIPHERAL NEUROPATHY
(East Carolina University, 2019-07-15)With the advancement of chemotherapy drugs, the general life expectancy of cancer patients has drastically improved. However, persistent side effects, such as chemotherapy-induced peripheral neuropathy (CIPN), often severely ...