Browsing Pharmacology and Toxicology by Subject "[Delta]-catenin/NPRAP"

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  • Identification of E2F1 as a positive transcriptional regulator for delta-catenin 

    Kim, Kwonseop; Oh, Minsoo; Ki, Hyunkyoung; Wang, Tao; Bareiss, Sonja; Fini, M. Elizabeth; Li, Dawei; Lu, Qun (East Carolina University, 2008-05-02)
    Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ...

  • Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover 

    Kim, Jin-Sook; Bareiss, Sonja; Kim, Kyung Keun; Tatum, Rodney; Han, Jeong-Ran; Jin, Yun Hye; Kim, Hangun; Lu, Qun; Kim, Kwonseop (East Carolina University, 2006-12-29)
    Although delta-catenin/neural plakophilin-related armadillo protein (NPRAP) was reported to interact with presenilin-1 (PS-1), the effects of PS-1 on delta-catenin have not been established. In this study, we report that ...