Browsing by Title
Now showing items 2941-2960 of 6589
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"I am still negative": Female sex workers' perspectives on uptake and use of daily pre-exposure prophylaxis for HIV prevention in South Africa.
(2019-04)Women remain highly vulnerable to HIV infection in sub-Saharan Africa, with female sex workers (FSWs) facing some of the highest rates of HIV. Oral pre-exposure prophylaxis (PrEP) has the potential to reduce new infections ... -
I Might Be Wrong ; and, As If It Was Made of Glass
(East Carolina University, 2012)These two stories of exceptional length feature narrators whose idiosyncratic moral dilemmas are indicative of larger social ills. Instead of the traditional epiphany so prevalent in 20th Century short stories, the characters ... -
"I Thought You Loved Me too?": Outcomes of Discrepant Involvement in Romantic Relationships
(2018-12-21)As romantic relationships begin and evolve, it is sometimes the case that partners are discrepant in their attraction to, love for, and commitment to each other. Data were collected from 460 undergraduates who completed ... -
I want to survive and thrive: diet and physical activity recommendations for Breast Cancer Survivors
(2018-09)In this article, we review current diet and physical activity recommendations for long-time survivors of breast cancer. We also hear the voice of a survivor and her response to the diagnosis of a postmenopausal breast ... -
Idempotents in Cyclic Codes
(East Carolina University, 2012)Cyclic codes give us the most probable method by which we may detect and correct data transmission errors. These codes depend on the development of advanced mathematical concepts. It is shown that cyclic codes, when viewed ... -
Identification and Characterization of alcR, a Gene Encoding an AraC-Like Regulator of Alcaligin Siderophore Biosynthesis and Transport in Bordetella pertussis and Bordetella bronchiseptica
(East Carolina University, 1998-02)A Bordetella bronchiseptica iron transport mutant was isolated following an enrichment procedure based on streptonigrin resistance. The mutant displayed a growth defect on iron-restricted medium containing ferric alcaligin ... -
Identification and characterization of iron-regulated Bordetella pertussis alcaligin siderophore biosynthesis genes.
(East Carolina University, 1996-08)Bordetella bronchiseptica mutants BRM1, BRM6, and BRM9 fail to produce the native dihydroxamate siderophore alcaligin. A 4.5-kb BamHI-SmaI Bordetella pertussis genomic DNA fragment carried multiple genes required to restore ... -
Identification and Characterization of Optimal Gene Expression Markers for Detection of Breast Cancer Metastasis
(East Carolina University, 2005-08)Sentinel lymph node (SLN) status is highly predictive of overall axillary lymph node involvement in breast cancer. Historically, SLN-positive patients have undergone axillary lymph node dissection in a second ... -
Identification and mapping of two divergent, unlinked major histocompatibility complex class II B genes in Xiphophorus fishes.
(East Carolina University, 1998-08)We have isolated two major histocompatibility complex (MHC) class II B genes from the inbred fish strain Xiphophorus maculatus Jp 163 A. We mapped one of these genes, designated here as DXB, to linkage group III, linked ... -
Identification of a circular intermediate in the transfer and transposition of Tn4555, a mobilizable transposon from Bacteroides spp.
(East Carolina University, 1993-05)Transmissible cefoxitin (FX) resistance in Bacteroides vulgatus CLA341 was associated with the 12.5-kb, mobilizable transposon, Tn4555, which encoded the 13-lactamase gene cfxA. Transfer occurred by a conjugation-like ... -
Identification of a novel Leucine-rich repeat protein and candidate PP1 regulatory subunit expressed in developing spermatids
(East Carolina University, 2008-01-31)Background: Spermatogenesis is comprised of a series of highly regulated developmental changes that transform the precursor germ cell into a highly specialized spermatozoon. The last phase of spermatogenesis, termed ... -
Identification of a Potential RNAzyme in Brucella abortus with Heme-Dependent Peroxidase Activity
(East Carolina University, 2020-11-19)Bovine brucellosis is of significant concern to the U.S. cattle industry and has not been controlled by vaccination in some areas of the world. The inability to control this pathogen is currently a serious public health ... -
Identification of Biomarkers in Non-Small Cell Lung Cancer Patients Treated with PD-1 Monoclonal Antibody Immunotherapy
(East Carolina University, 2018-08-22)Cancer immunotherapy works by taking a patient's existing immune system and priming it to recognize cancer cells in order for immune cells to mount an effective response to the disease. This is a less invasive means of ... -
Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5
(2011)Background Within erythrocytes (RBCs), cAMP levels are regulated by phosphodiesterases (PDEs). Increases in cAMP and ATP release associated with activation of β-adrenergic receptors (βARs) and prostacyclin receptors ... -
Identification of Damaged DNA Adducts from Exposure to Benzo[a]pyrene in the TP53 Gene
(2015)Benzo[a]pyrene is a carcinogen associated with tobacco smoke that can damage DNA after it is metabolized into highly reactive forms. Identifying the resulting DNA adducts can give greater insight into the mutations that ... -
Identification of E2F1 as a positive transcriptional regulator for delta-catenin
(East Carolina University, 2008-05-02)Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ... -
Identification of Extracellular d-Catenin Accumulation for Prostate Cancer Detection
(East Carolina University, 2009-03-01)BACKGROUND—Prostate cancer is the second leading cause of cancer death in men, and early detection is essential to reduce mortality and increase survival. δ-Catenin is a unique β-catenin superfamily protein primarily ... -
Identification of Factors Associated with the Development and Decay of Heterologous Tolerance to Morphine in the Guinea Pig
(East Carolina University, 2016-05-03)It is believed that the heterologous tolerance that develops upon chronic exposure to morphine is the result of adaptive changes in the cellular signaling pathways associated with the [mu] opioid receptor. Proposed adaptive ... -
IDENTIFICATION OF FACTORS THAT CONTRIBUTE TO AN INCREASE IN LIFEGUARD COMPLACENCY
(East Carolina University, 2011)The purpose of this thesis was to identify factors that predict lifeguard complacency in an effort to increase overall vigilance while lifeguarding. Three research questions were explored: (a) what factors contribute to ... -
IDENTIFICATION OF GEOCHEMICAL TRACERS WITHIN BIOMINERALS OF JUVENILE AND LARVAL MERCENARIA MERCENARIA : IMPLICATIONS FOR MODELING LARVAL DISPERSAL
(East Carolina University, 2013)This study was designed to investigate the application of geochemical signals within biominerals to identify site fidelity and natal origin of the commercially valuable bivalve Mercenaria mercenaria. My first study ...