Browsing by Author "Gambino, Mario W."

Now showing items 1-2 of 2

  • Inhibition of Cdk2 kinase activity selectively targets the CD44/CD24 stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells 

    Opyrchal, Mateusz; Salisbury, Jeffrey L.; Iankov, Ianko; Goetz, Matthew P.; McCubrey, James A.; Gambino, Mario W.; Malatino, Lorenzo; Puccia, Giuseppe; Ingle, James N.; Galanis, Evanthia; D'Assoro, Antonino B. (2014-09)
    Inflammatory breast cancer (IBC) is an angioinvasive and most aggressive type of advanced breast cancer characterized by rapid proliferation, chemoresistance, early metastatic development and poor prognosis. IBC tumors ...

  • NOTCH3 Expression Is Linked to Breast Cancer Seeding and Distant Metastasis 

    Leontovich, Alexey A.; Jalalirad, Mohammad; Salisbury, Jeffrey L.; Mills, Lisa; Haddox, Candace; Schroeder, Mark; Tuma, Ann; Guicciardi, Maria E.; Zammataro, Luca; Gambino, Mario W.; Amato, Angela; Di Leonardo, Aldo; McCubrey, James; Lange, Carol A.; Liu, Minetta; Haddad, Tufia; Goetz, Matthew; Boughey, Judy C.; Sarkaria, Jann; Wang, Liewei; Ingle, James N.; Galanis, Evanthia; D’Assoro, Antonino B. (2018-09-04)
    Background: Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. ...