Now showing items 1-1 of 1

  • Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening 

    Canugovi, Chandrika; Stevenson, Mark D.; Vendrov, Aleksandr E.; Hayami, Takayuki; Robidoux, Jacques; Xiao, Han; Zhang, You-Yi; Eitzman, Daniel T.; Runge, Marschall S.; Madamanchi, Nageswara R. (2019-08-02)
    Aging is characterized by increased aortic stiffness, an early, independent predictor and cause of cardiovascular disease. Oxidative stress from excess reactive oxygen species (ROS) production increases with age. Mitochondria ...