Browsing by Subject "Aerobic capacity"
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Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ... -
Effects of Aerobic Capacity Phenotype on Adaptive Responses to Ischemic Stress
(East Carolina University, 2009)Ischemic disease leads to increased tissue stress by decreasing supply of nutrients adequate to meet energy demands. To maintain functionality, compensatory mechanisms for diminished vascular supply are induced by numerous ...