Browsing by Subject "Biology, Neuroscience"
Now showing items 1-15 of 15
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The Biochemical Characterization Of Neuronal K+ Channel N-Glycans And Their Role In Regulating K+ Channel Function
(East Carolina University, 2009)The Kv3 and Kv1 subfamilies of voltage–gated K+ channels are critical components which contribute to action potential repolarization throughout the central nervous system. Here, it was shown that both absolutely conserved ... -
Brainstorm Newsletter
(East Carolina University, 2010-04-30)Inaugural newsletter of the Neuroscience Program. -
Changes in zebra finch central nervous system morphology associated with developmental cannabinoid exposure
(East Carolina University, 2012)Adolescent CNS development is a highly organized, coordinated process that is both genetically and environmentally influenced, and is characterized by a period of dynamic, activity-dependent changes in synaptic connectivity. ... -
CHARACTERIZATION OF MIGRATING NEURAL CREST CELLS FROM HINDBRAIN EXPLANTS IN ZEBRAFISH
(East Carolina University, 2010)Our lab was interested in creating a reproducible mechanism for obtaining neural crest cells in culture from cultured hindbrain explants of zebrafish. We have characterized the population of cells migrating from the ... -
Comparison of tolerance characteristics in the guinea pig following chronic in-vivo exposure to opioid versus cannabinoid receptor agonists
(East Carolina University, 2010)Few studies have compared the nature of tolerance that develops following chronic in vivo opioid treatment with that which develops after chronic cannabinoid exposure in the same tissue and species. Based on similarities ... -
Creating a Shared Neuroscience Collection Development Policy
(2012-08)At East Carolina University (ECU), Joyner Academic and Laupus Health Sciences Libraries collaborated on a shared Neuroscience collection development policy, primarily as a reaction to state-level budget cuts. The policy ... -
Developmental lead exposure and the exacerbation of Alzheimer's pathology: an immunological analysis
(East Carolina University, 2014)Early neuroimmune dysfunction may play a driving role in the etiopathology of Alzheimer's disease (AD), stemming from the hypothesis that many late-stage adult diseases have an early-life basis. Here we explore whether ... -
Dopaminergic modulation of the autonomic nervous system: in vitro and in vivo evidence from the mouse
(East Carolina University, 2012)Central nervous system (CNS) function depends on both the connections between the underlying neurons and neural circuits and their activity. Neuronal activity in turn can be classified as neurotransmission and neuromodulation, ... -
Generators of mammalian vestibular surface responses to head motion
(East Carolina University, 2012)The linear vestibular sensory evoked potential (VsEP) is thought to be the compound electrical response of peripheral macular neurons and central neural relays, and as such used to directly assess macular function. The ... -
Increased Antagonist Coactivation-Related Hamstring Torque Reduces Maximal Knee Extension Torque in Healthy Old Adults
(East Carolina University, 2010)As humans age, the ability to produce maximal voluntary torque decreases due to muscle atrophy (sarcopenia) and it is also known that advancing age alters the neural control of voluntary movement. One manifestation of the ... -
Individual Differences in Error Related Processing of Expectancy Violations
(East Carolina University, 2012)Electrophysiological investigations of brain processing of feedback reveal that the anterior cingulate cortex is important in monitoring for behavioral errors. The feedback related negativity (FRN) is an event related ... -
LIBotomy: Creating a Shared Neuroscience Collection Development Policy
(2011-10-11)Purpose: This poster examines the collaboration between the Joyner Academic and Laupus Health Sciences Library at East Carolina University to establish a shared Neuroscience Collection Development Policy. Setting/ ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
The role of mediators of neuronal plasticity in the circadian regulation of suprachiasmatic nucleus by light
(East Carolina University, 2009)Circadian rhythms are highly conserved physiological functions that are present in almost all living organisms. In mammals, circadian rhythms are synchronized to the environmental light:dark cycle by daily adjustments in ... -
The significance of mirna pathway in peripheral nerve regeneration following sciatic nerve injury.
(East Carolina University, 2012)microRNAs (miRNAs) are small (21-23 nucleotides) single-stranded RNAs that play important roles in post-transcriptional regulation of gene expression. The binding of miRNA to its specific target mRNAs at 3' UTR causes ...