Now showing items 1-3 of 3

  • delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles 

    Zeng, Yan; Abdallah, Agustin; Lu, Jian-Ping; Wang, Tao; Chen, Yan-Hua; Terrian, David M.; Kim, Kwonseop; Lu, Qun (East Carolina University, 2009-03-10)
    Background: delta-Catenin is a unique member of delta-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, delta-catenin is upregulated in human prostatic adenocarcinomas, ...
  • Identification of E2F1 as a positive transcriptional regulator for delta-catenin 

    Kim, Kwonseop; Oh, Minsoo; Ki, Hyunkyoung; Wang, Tao; Bareiss, Sonja; Fini, M. Elizabeth; Li, Dawei; Lu, Qun (East Carolina University, 2008-05-02)
    Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ...
  • Identification of Extracellular d-Catenin Accumulation for Prostate Cancer Detection 

    Lu, Qun; Zhang, Jiao; Allison, Ron R.; Gay, Hiram A.; Yang, Wan-Xi; Bhowmick, Neil; Frelix, Gloria; Shapell, Scott; Chen, Yan-Hua (East Carolina University, 2009-03-01)
    BACKGROUND—Prostate cancer is the second leading cause of cancer death in men, and early detection is essential to reduce mortality and increase survival. δ-Catenin is a unique β-catenin superfamily protein primarily ...