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    • The RXR-alpha C-terminus T462 is a NMR sensor for coactivator peptide binding 

      Lu, Jianyun; Chen, Minghe; DeKoster, Gregory T.; Cistola, David P.; Li, Ellen (East Carolina University, 2008-02-22)
      The C-terminal activation function-2 (AF-2) helix plays a crucial role in retinoid X receptor alpha (RXRα)-mediated gene expression. Here, we report a nuclear magnetic resonance (NMR) study of the RXRα ligand-binding domain ...