Browsing by Subject "Gene expression"
Now showing items 1-20 of 26
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The AraC-Like Transcriptional Regulator DhbR Is Required for Maximum Expression of the 2,3-Dihydroxybenzoic Acid Biosynthesis Genes in Brucella abortus 2308 in Response to Iron Deprivation
(East Carolina University, 2008-03)Phenotypic evaluation of isogenic mutants derived from Brucella abortus 2308 indicates that the AlcR homolog DhbR (2,3-dihydroxybenzoic acid [2,3-DHBA] biosynthesis regulator) modulates the expression of the genes involved ... -
Changes in muscle strength, muscle fibre size and myofibrillar gene expression after immobilization and retraining in humans
(East Carolina University, 2000-01)1. Changes in muscle strength, vastus lateralis fibre characteristics and myosin heavychain (MyoHC) gene expression were examined in 48 men and women following 3 weeks of knee immobilization and after 12 weeks of retraining ... -
Characterizing the vegetative phenotype of fzt maize mutant
(East Carolina University, 2012)microRNAs are short, non-coding RNA strands that regulate gene expression post-transcriptionally in all multicellular organisms. miRNAs begin as a hairpin in the nucleus. The primary miRNA (pri-miRNA) and preliminary ... -
Comparison of the exoS Gene and Protein Expression in Soil and Clinical Isolates of Pseudomonas aeruginosa
(East Carolina University, 2001-04)Exoenzyme S (ExoS) is translocated into eukaryotic cells by the type III secretory process and has been hypothesized to function in conjunction with other virulence factors in the pathogenesis of Pseudomonas aeruginosa. ... -
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ... -
Connecting Mutations of the RNA Polymerase II C-Terminal Domain to Complex Phenotypic Changes Using Combined Gene Expression and Network Analyses
(2010)The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is essential for mRNA synthesis and processing, through coordination of an astounding array of protein-protein interactions. ... -
Deep Sequencing Reveals Transcriptome Re-Programming of Cells to the Elicitation with Methyl Jasmonate
(2013)Background Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ... -
A depauperate immune repertoire precedes evolution of sociality in bees
(2015-04-24)Background Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other ... -
Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ... -
DIFFERENTIAL GENE EXPRESSION IN THE BRAINS OF BEGGING POISON FROG TADPOLES
(East Carolina University, 8/5/2020)Parents often rely on offspring signals to adequately allocate resources to dependent offspring. The mimic poison frog, Ranitomeya imitator, has evolved elaborate parental care behaviors to raise their young. Their tadpoles ... -
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.
(East Carolina University, 1997-02)3T3-L1 preadipocytes ectopically expressing the mammalian RNA-binding protein Hel-N1 expressed up to 10-fold more glucose transporter (GLUT1) protein and exhibited elevated rates of basal glucose uptake. Hel-N1 is a member ... -
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ... -
The effects of sodium butyrate on Hox gene expression in a human colorectal adenocarcinoma cell line, HT29.
(East Carolina University, 2013)Hox genes are a subgroup of the large family of homeobox containing genes, known to pattern anterior/posterior and proximal/distal axes during embryonic development. More recently Hox gene research has focused on the role ... -
THE EVOLUTION OFHOX [sic] PARALOG GROUP 2 GENE EXPRESSION AND REGULATION IN THE JAPANESE MEDAKA
(East Carolina University, 2011)Hox paralog group 2 (PG2) genes are evolutionarily conserved developmental regulatory genes that function to specify rhombomere (r) and pharyngeal arch (PA) identities in animal embryos. Several rounds of whole genome ... -
A Functional Analysis of microRNAs in Nicotiana tabacum
(East Carolina University, 2012)MicroRNAs (miRNAs) are a newly discovered class of endogenous post-transcriptional gene regulators that are typically 20-22 nucleotides in length that do not code for proteins. MiRNAs regulate gene expression by either ... -
Gene Expression and the Evolution of Reduced Sexual Dimorphism in a Threespine Stickleback Color Trait
(East Carolina University, 2017-01-03)Elucidating the processes and mechanisms responsible for sexual dimorphism has been a central task for evolutionary biologists since Darwin first proposed the concept of sexual selection. However, our understanding of the ... -
Gene Expression Divergence Between Zebra Finch (Taeniopygia Guttata) Subspecies And Gene Regulation In Hybrids
(East Carolina University, 2015)Since the publication of Mayr's Systematics and the Origin of Species, birds have been important model organisms for studies regarding evolutionary processes such as sexual selection and speciation. In this study, I will ... -
Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database
(2011)A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ... -
Hox Gene Expression During Oreochromis niloticus Pharyngeal Arch Development : Discovering the Hox Code
(East Carolina University, 2010)Hox genes encode transcription factors and have been extensively studied by evolutionary and developmental biologists. Hox genes are responsible for determining specific regional identities along the anterior-posterior and ... -
Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass
(2016-11-08)Abstract Background Switchgrass (Panicum virgatum L.) is a warm-season perennial grass that can be used as a second generation bioenergy crop. However, foliar fungal ...