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    • Resolving the Role of POU1F1 in Human Growth Hormone Locus Activation 

      Hunsaker, Tamra Leigh (East Carolina University, 2012)
      The human growth hormone gene ( hGH-N) is regulated by a distal locus control region (LCR) composed of five deoxyribonuclease I hypersensitive sites (HSs). The region encompassing HSI and HSII contains the predominant ...