Now showing items 1-1 of 1

  • Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis 

    Nelson, Nadine; Xiang, Shengyan; Zhang, Xiaohong; Gilvary, Danielle; Djeu, Julie; Husain, Kazim; Malafa, Mokenge; Vohra, Nasreen; Pilon-Thomas, Shari; Ghansah, Tomar (2015-01)
    Background Maintenance of T cell immune homeostasis is critical for adequate anti-tumor immunity. The transcription factor Ikaros is essential for lymphocyte development including T cells. Alterations in Ikaros expression ...