Browsing by Subject "Non-insulin-dependent diabetes"
Now showing items 1-5 of 5
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African American Women with Type 2 Diabetes : A Biopsychosocial-Spiritual Approach
(East Carolina University, 2010)This dissertation consists of two articles written to address the context of type 2 diabetes care in African American women. In addition, the proposal and required Institutional Review Board (IRB) documentation are included ... -
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
(East Carolina University, 2011)Mitochondrial respiratory capacity and oxidative stress have been implicated in the development of insulin resistance (IR) and type II diabetes. A causative role of mitochondrial oxidative stress in the etiology of ... -
Potential Mechanisms for Amelioration of Type 2 Diabetes Following Bariatric Surgery
(East Carolina University, 2011)Severe obesity and Type 2 Diabetes (T2DM) are worldwide health concerns reaching epidemic proportions. Roux-en-Y gastric bypass (RYGB) has been shown to elicit a rapid and durable improvement and/or remission of T2DM in ... -
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.
(East Carolina University, 1992-02)A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal ... -
A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats
(East Carolina University, 2010)Energy balance is considered a fundamental requirement of life forms from single cell organisms to higher mammals such as humans. Unfortunately, our species has also discovered the detrimental metabolic responses to excess ...