Browsing by Subject "Rho GTPases"
Now showing items 1-2 of 2
-
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants
(East Carolina University, 2008-07)Many chemotherapy drugs are known to cause significant clinical neurotoxicity, which can result in the early cessation of treatment. To identify and develop more effective means of neuroprotection it is important to ... -
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ...