Browsing by Subject "Sphingolipid, cancer, chemotherapy resistance, glucosylceramide synthase, acid ceramidase, sphingosine kinase, viability assay, LoVo, HT-29, pharmacological inhibition"
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(East Carolina University, 2019-05-03)Alterations in sphingolipid (SL) metabolism can contribute to cancer progression as well as chemotherapy resistance. Thus, the enzymes of SL metabolism are exploitable targets for the development of novel therapeutics. ...