Browsing by Subject "Stem Cells"

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  • Genetic and hypoxic effects on germline tumor development in caenorhabditis elegans 

    Datla, Udaya Sree (East Carolina University, 2013)
    The process of differentiation of stem cells to committed, progenitor specific cell types is well studied but the reverse process of the dedifferentiation of these committed cells back to the undifferentiated state still ...

  • Targeting the leukemic stem cell: the Holy Grail of leukemia therapy 

    Misaghian, Negin; Ligresti, Giovanni; Steelman, L. S.; Bertrand, Fred E.; Basecke, Jorg; Libra, Massimo; Nicoletti, Ferdinando; Stivala, F.; Milella, Michele; Tafuri, A.; Cervello, Melchiorre; Martelli, Alberto M.; McCubrey, James A. (East Carolina University, 2009-01)
    Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biological properties have been elucidated, including their distinct replicative properties, cell surface phenotypes, their ...