Browsing by Subject "Stem cells"
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Drosophila Ovarian Stem Cell Establishment is Regulated by Nuclear Hormone Receptor ftz-f1
(East Carolina University, 2017-06-28)Stem cells are a fundamental underpinning of tissue biology. Loss of the self-renewing function of stem cells leads to conditions such as infertility and tissue wasting. Stem cells integrate a variety of signals to maintain ... -
A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis
(2016-08)Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While the transcriptional targets of ecdysone ... -
The Role of Pre-Replication Complex Proteins in Drosophila Ovarian Stem Cell Maintenance and Proliferation
(East Carolina University, 2017-05-05)Cancer stem cells (CSCs) may hold the key to advances in cancer research. Like adult tissue-specific stem cells, CSCs are able to self-renew and last a lifetime. These shared characteristics can thus be used to help learn ...