Browsing by Subject "VISP"
Now showing items 1-4 of 4
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A Candidate Gene Study: Finding Associations between Recurrent Stroke and Genetic Variants of Five Folate-Mediated One Carbon Metabolism Pathway Genes
(East Carolina University, 2019-04-25)Stroke is the second leading cause of death in the world and fifth in the United States. Both in the United States and worldwide, stroke is the leading cause of disability. Stroke is a cerebrovascular event which results ... -
Fine-mapping a novel locus on Chromosome 1 for associations with recurrent stroke
(East Carolina University, 2019-07-18)INTRODUCTION: Stroke is a complex, multifactorial cerebrovascular disease that afflicts millions of individuals both nationally and globally. Of the annual 795,000 stroke incidents, approximately 185,000 are recurrent ... -
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial
(2014-08)Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study ... -
Investigating Novel Chromosome 2 Genetic Variants Associated with Recurrent Stroke
(East Carolina University, 2019-07-18)As the fifth leading cause of death and leading cause of long-term disability, stroke affects 795,000 individuals annually in the United States alone. Recurrent stroke, which is far more deadly and disabling, accounts for ...