Browsing by Subject "Zebrafish"
Now showing items 1-6 of 6
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Adamts9 is necessary for ovarian development in zebrafish
(East Carolina University, 2020-05-04)Expression of adamts9 (A disintegrin and metalloprotease with thrombospondin type-1 motif, member 9) increases dramatically in the somatic cells surrounding oocytes during ovulation in vertebrates from zebrafish to human. ... -
Analysis of scn5Laa and scn5Lab Gene Function in Danio rerio (Zebrafish) Heart Development through TALENs/CRISPR-CAS9-mediated Gene Knockout
(East Carolina University, 2015)Research in our laboratory is focused on understanding the molecular developmental genetic effects of crude oil exposure on vertebrate embryogenesis. Our research has demonstrated that exposure of zebrafish embryos to ... -
Development of an Optogenetic Tool for Targeted Sensory Hair Cell Ablation in Zebrafish
(East Carolina University, 2022-04-28)Mechanosensory hair cells convert mechanical information into neuronal signals. Mutations in the genes required for hair cell function cause deafness and lead to the degeneration of sensory hair cells. Mammals are unable ... -
The Effects of Crude Oil and Chemical Dispersant Exposure on Danio rerio (zebrafish) Embryonic Development
(East Carolina University, 2014)Crude oil has been shown to cause defects in cardiovascular development in a variety of teleost species. We used the zebrafish, Danio rerio as a model to test the effects of oil and dispersant on cardiac development and ... -
PROLACTIN FUNCTION IN ZEBRAFISH DEVELOPMENT
(East Carolina University, 2010)Extensive studies have implicated a myriad of functional roles for prolactin (PRL) and prolactin receptor (PRLR) across a variety of adult vertebrate species. However, much less is known about the physiological role(s) of ... -
Relationship of N-glycans to Neuronal Dysfunction
(East Carolina University, 2019-06-07)N-glycosylation is important in regulating protein activity and serves several vital roles contributing to protein folding, protein assembly, stability, and interactions. Changes in branching of N-glycans are linked to ...