Now showing items 1-3 of 3

    • Acidosis Activated GPR68 Promotes Vascular Smooth Muscle Cell Growth 

      Morgan, Joshua S (East Carolina University, 2020-12-17)
      Cardiovascular disease (CVD) is the primary cause of death in the United States and worldwide. Localized extracellular acidosis has been theorized as a possible contributor to CVD pathogenesis, but its precise impact remains ...
    • Control of Vascular Smooth Muscle Cell Growth by Connexin 43 

      Joshi, Chintamani N.; Martin, Danielle N.; Shaver, Patti; Madamanchi, Chaitanya; Muller-Borer, Barbara J.; Tulis, David A. (2012-06)
      Connexin 43 (Cx43), the principal gap junction protein in vascular smooth muscle cells (VSMCs), regulates movement of ions and other signaling molecules through gap junction intercellular communication (GJIC) and plays ...
    • Phosphodiesterases Regulate BAY 41-2272-Induced VASP Phosphorylation in Vascular Smooth Muscle Cells 

      Adderley, Shaquria P.; Joshi, Chintamani N.; Martin, Danielle N.; Tulis, David Anthony (2012-02)
      BAY 41-2272 (BAY), a stimulator of soluble guanylyl cyclase, increases cyclic nucleotides and inhibits proliferation of vascular smooth muscle cells (VSMCs). In this study, we elucidated mechanisms of action of BAY in its ...