Browsing Physiology by Author "Wingard, Christopher J."
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Augmented coronary vascular smooth muscle response to endothelin-1 exacerbates cardiac injury following pulmonary exposure to engineered nanomaterials
Thompson, Leslie Charles (East Carolina University, 2014)Multi-walled carbon nanotubes (MWCNT) and 60-carbon fullerenes (C60) are important engineered nanoparticles (ENP) used across industry. Exposure to ENP potentially promotes cardiovascular detriments. The hypotheses that ... -
Expansion of cardiac ischemia/reperfusion injury after instillation of three forms of multi-walled carbon nanotubes
Urankar, Rakhee N.; Lust, Robert M.; Mann, Erin; Katwa, Pranita; Wang, Xiaojia; Podila, Ramakrishna; Hilderbrand, Susana C.; Harrison, Benjamin S.; Chen, Pengyu; Ke, Pu Chun; Rao, Apparao M.; Brown, Jared; Wingard, Christopher J. (2012)Background The exceptional physical-chemical properties of carbon nanotubes have lead to their use in diverse commercial and biomedical applications. However, their utilization has raised concerns about human exposure ... -
Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus)
Yenugu, Suresh; Chintalgattu, Vishnu; Wingard, Christopher J.; Radhakrishnan, Yashwanth; French, Frank S.; Hall, Susan H. (East Carolina University, 2006-02-04)Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract ... -
Impact of pulmonary exposure to gold core silver nanoparticles of different size and capping agents on cardiovascular injury
Holland, Nathan A.; Thompson, Leslie C.; Vidanapathirana, Achini K.; Urankar, Rahkee N.; Lust, Robert M.; Fennell, Timothy R.; Wingard, Christopher J. (2016-08-24)Background:The uses of engineered nanomaterials have expanded in biomedical technology and consumer manufacturing. Furthermore, pulmonary exposure to various engineered nanomaterials has, likewise, demonstrated the ability ...