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The â€œGoldilocks Zoneâ€? from a redox perspectiveâ€”Adaptive vs. deleterious responses to oxidative stress in striated muscle
Consequences of oxidative stress may be beneficial or detrimental in physiological systems. An organ system's position on the “hormetic curve” is governed by the source and temporality of reactive oxygen species (ROS) ...
Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment
Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role ...
Why Does Exercise â€œTriggerâ€? Adaptive Protective Responses in the Heart?
Numerous epidemiological studies suggest that individuals who exercise have decreased cardiac morbidity and mortality. Pre-clinical studies in animal models also find clear cardioprotective phenotypes in animals that ...