Browsing Surgery by Author "Meelheim, Diane"
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An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.
Dohm, G. Lynis; Tapscott, Edward B.; Pories, Walter J.; Dabbs, David J.; Flickinger, Edward G.; Meelheim, Diane; Fushiki, Tohru; Atkinson, Samuel M.; Elton, Charles W.; Caro, Jose F. (East Carolina University, 1988-08)We have developed an in vitro muscle preparation suitable for metabolic studies with human muscle tissue and have investigated the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on glucose transport. ... -
Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.
Sinha, Madhur K.; Taylor, Lucy G.; Pories, Walter J.; Flickinger, Edward G.; Meelheim, Diane; Atkinson, Samuel M.; Sehgal, Narinder S.; Caro, Jose F. (East Carolina University, 1987-10)We have tested the hypothesis that in vitro exposure of insulin- resistant adipocytes with insulin results in improved insulin action. A primary culture system of adipocytes from obese subjects with ...