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Now showing items 11-20 of 48
Effect of Duodenal-Jejunal Bypass on Skeletal Muscle Insulin Signaling in Goto-Kakizaki Rats
(East Carolina University, 2009)
Gastric bypass surgery (RYGBP) for the treatment of obesity has proven to clinically reverse type 2 diabetes mellitus. RYGBP involves both gastric reduction and bypass of the proximal small intestine. Duodenal-Jejunal ...
Phylogenetics and Systematics of the Millipede genus Brachycybe Wood, 1864 (Platydesmida: Andrognathidae)
(East Carolina University, 2010)
The genus Brachycybe Wood, 1864 (Platydesmida: Andrognathidae) belongs to an ancient millipede lineage that has persisted since the Miocene. The group displays a Holarctic distribution with species in the eastern Nearctic, ...
Identification, Characterization, and Abiotic Stress Analysis of microRNAs in Nicotiana tabacum
(East Carolina University, 2010)
microRNAs (miRNAs) are non-coding RNAs with short sequences that negatively regulate gene expression at the post-transcriptional levels by either binding to mRNAs for degradation, or by inhibiting protein translation. ...
Psf2, a member of the heterotetrameric GINS Complex, plays a role in cell cycle progression and maintenance of genomic integrity
(East Carolina University, 2010)
Multiple proteins are involved in the complete and accurate replication of the genome during S phase of the cell cycle. At the G1/S phase transition, the heterotetrameric GINS complex is recruited to the origin, and ...
LOCALIZATION AND CHANGES OF NUCLEAR PROGESTERONE RECEPTORS IN ZEBRAFISH OOCYTES AND ADJACENT FOLLICULAR CELLS
(East Carolina University, 2010)
The nuclear progesterone receptor (Pgr) is one of the major mediators for progestin signaling during oocyte ovulation in vertebrates. However, any roles Pgr may play in oocyte growth, and especially in the final oocyte ...
Interaction and Functional Analysis of Drosophila Mcm10
(East Carolina University, 2010)
In eukaryotic cells, DNA replication and the subsequent packaging of DNA into specific chromatin states are essential processes for the transmission of genetic material and genomic stability which may be linked by interactions ...
Hox Gene Expression During Oreochromis niloticus Pharyngeal Arch Development : Discovering the Hox Code
(East Carolina University, 2010)
Hox genes encode transcription factors and have been extensively studied by evolutionary and developmental biologists. Hox genes are responsible for determining specific regional identities along the anterior-posterior and ...
Characterization of the GINS subunit psf1 in Drosophila Melanogaster
(East Carolina University, 2010)
GINS (Go Ichi Ni San; 5,1,2,3 in Japanese) is a heterotetrameric protein complex known to be essential for the establishment of DNA replication forks and the progression of the replisome. The GINS complex is known to be ...
Characterization of Site-Directed Mutants in the Cytochrome c-550 Protein of Photosystem II
(East Carolina University, 2010)
Photosynthesis is the process by which cyanobacteria, algae, and higher plants convert light energy to chemical energy via the biosynthesis of carbohydrates. Photosystem II is a multi-protein/pigment complex embedded in ...
Characterization of Two Novel Mutants of DNA Polymerase Delta in Drosophila melanogaster
(East Carolina University, 2011)
DNA is the genetic material for all living organisms which is constantly being unpackaged, replicated and repackaged. The replication of this genetic material involves numerous different proteins; however, DNA polymerase ...