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Characterizing the Expression Pattern of miR167-Regulated ZmArf3 and ZmArf30 in Maize Inflorescences
(East Carolina University, 2014)
Plant growth and development depends on the activity of meristems, pools of stem cells that generate leaves and other organs. Maize (corn) produces two inflorescences, the tassel and ear, which are patterned by a series ...
Physiological Studies of Alkaliphilic Anaerobic Organotrophs in a Serpentinizing Subsurface Habitat
(East Carolina University, 2014)
Microbial habitats in serpentinizing ultramafic rocks represent one of the largest, yet least understood portions of the biosphere, with potentially major consequences for global biogeochemical cycles. Serpentinization is ...
The Role of Transcription Factors Snail and Slug in Cardiac Myofibroblasts
(East Carolina University, 2014)
CCardiac fibrosis is a major facet contributing to cardiac dysfunction following a myocardial infarction. Persistent and excessive collagen deposition via cardiac myofibroblasts is the hallmark of cardiac fibrosis. Cardiac ...
Fesselin, an intrinsically disordered smooth muscle protein, organizes and stabilizes actin-myosin and myosin
(East Carolina University, 2014)
Fesselin is an intrinsically disordered protein that is known to bind a large variety of cytoskeletal proteins. The proteins fesselin is known to bind include: actin (Leinweber et al. 1999), [alpha]-actinin (Pham et al. ...
Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)
MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ...
Investigating the Interaction of RecQL4 and Mcm10 in Drosophila melanogaster
(East Carolina University, 2014)
Accurate duplication and regulation of the eukaryotic genome requires precise coordination among multiple replication factors. RecQL4, the least characterized RecQ protein, is a 1208 amino acid protein containing a centrally ...
Analysis of Myopodin in Hela Cervical Carcinoma Cells
(East Carolina University, 2014)
Synaptopodin-2 is a proline-rich, actin-binding protein that exists in many isoforms. Due to its large proline content, synaptopodin-2 exists in a naturally unfolded state and possesses the characteristics of a hub protein. ...
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)
During cell stress many biochemical processes are shut down. For
example, global mRNA translation initiation is inhibited due to the
disruption of the cap-dependent mRNA recruitment mechanism. One
specific example of ...
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)
There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ...
[Delta]-catenin: implications in prostate cancer progression
(East Carolina University, 2014)
Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of cancer death among men in the US. Due to the advances in research, the ability to detect and cure PCa has improved and led to ...