Browsing Dissertations by Title
Now showing items 291-310 of 1044
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Effects of Exogenous and Autocrine Growth Hormone (hGH) on Prostate Cancer Cell Function
(East Carolina University, 2012)Human growth hormone (hGH) is a major product of the anterior pituitary. In addition to its endocrine activities, hGH overexpression in extra-pituitary tissues has been correlated with the oncogenic behavior of these ... -
Effects of Insulin Sensitivity Modulators on the Mitochondrial Fate of Oxygen in Skeletal Muscle
(East Carolina University, 2010)Increasingly, reactive oxygen species (ROS) are implicated in the development of insulin resistance. To test the hypothesis that modulators of insulin sensitivity (i.e., metformin, ovarian sex steroids and exercise training) ... -
Effects of Land Use Change on Juvenile Fishes, Blue Crab, and Brown Shrimp Abundance in the Estuarine Nursery Habitats of North Carolina
(East Carolina University, 2011)The U.S. coastal region is home to more than half of the American population. Also, the coastal counties' population is growing much faster than that of inland counties. With a high density and an increasing population, ... -
Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle
(East Carolina University, 2013)Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle by Lance M. Bollinger November, 2013 Director of Thesis/Dissertation: Jeffrey J. Brault Major Department: Kinesiology ... -
The effects of presentation rate on semantic, syntactic, and orthographic processing and relationship to reading fluency in children
(East Carolina University, 2011)Reading fluency is the connection between reading decoding and reading comprehension. A child becomes fluent between second and third grade (Coltheart, 1978). However, it is unknown if fluency is strictly the result of ... -
Effects of psychological stressors and [delta]⁹-THC acutely and chronically on zebra finch song behavior and dendritic spine density
(East Carolina University, 2020-06-22)This dissertation investigated song performance and dendritic spine density, following acute restraint stress in adult zebra finches and, following chronic mild stress and CB1 receptor partial agonist [delta]⁹-tetrahydrocannabinol ... -
The effects of reading acceleration on reading comprehension and decoding accuracy in high school students with reading disorders.
(East Carolina University, 2012)Reading disorders have been hypothesized to result from an asynchrony between speed of processing characteristics of auditory and visual systems involved in decoding. It is hypothesized that reading at faster rates can ... -
Effects of resveratrol and contractile activity in human skeletal muscle myotubes from severely obese individuals
(East Carolina University, 2016-07-25)The prevalence of obesity is exponentially increasing worldwide. Although strategies such as exercise, nutritional intervention, and pharmaceutical therapies including resveratrol have been extensively studied in lean or ... -
Effects of Word Type, Orthographic Type, and Word Length on Decoding and Spelling Abilities of Fourth Graders with and without Reading Impairments
(East Carolina University, 2014)The effects of word type (real, nonsense), orthographic type (phonetic, nonphonetic), and word length (1 to 5 syllables) on the decoding and spelling abilities (accuracy) of fourth-graders with and without reading impairments ... -
Electron Emission from Fast Proton and Carbon Ion Interactions with Gold Nanoparticles and Amorphous Solid Water
(East Carolina University, 2021-07-22)Widely used in the treatment of cancer, radiation therapy delivers a lethal dose of energy to malignant tissue. Modeling the deposition of energy in the interactions of the radiation with biological material is important ... -
Elucidating the Mechanism of Action of Unnatural Amino Acid Containing Antimicrobial Peptides in Membrane Environments
(East Carolina University, 2012)Organism resistance continues to develop to the currently available antimicrobial compounds necessitating the development of innovative new therapeutic compounds with different specificities and mechanisms of action that ... -
Elucidating the Mechanisms of Transthyretin Aggregation in Transthyretin Amyloidosis
(East Carolina University, 2018-07-24)Accumulation of insoluble aggregates (amyloids) is a characteristic feature of many neurodegenerative diseases including Alzheimer's disease and Parkinson's disease. Aggregation and deposition of Transthyretin (TTR) protein ... -
ELUCIDATION ON THE MECHANISM OF CAMKKα AS A PRO-GROWTH KINASE IN MOUSE SKELETAL MUSCLE
(East Carolina University, 2016-12-15)Type 2 diabetes affects ~25 million people in the U.S., and is the primary cause of non-traumatic lower limb amputation and the leading cause of blindness in adults. Major risk factors for the development of type 2 diabetes ... -
Emergence delirium subsequent to general anesthesia in service members who served during the global war on terrorism.
(East Carolina University, 2011)The primary aims of this study were to investigate, through active duty Army anesthesia provider's perceptions, the following: 1) the extent and seriousness of emergence delirium (ED) in service members; 2) effects of ED ... -
EMPHASIZING PROFESSIONALISM TO ADDRESS TEACHER TURNOVER AT DILLARD MIDDLE SCHOOL
(East Carolina University, 2017-04-19)The dissertation examines the effects professional learning communities can have on improving teacher retention in a high needs school. The goal is to positively impact teacher retention by emphasizing and encouraging ... -
Employee Assistance Program Utilization and User Satisfaction in an AbilityOne Program Compared to Non-AbilityOne Programs
(East Carolina University, 2011)The present study examines the effectiveness and utilization of an Employee Assistance Program (EAP) that was designed to serve 218 employees of an AbilityOne company whose mission it was "to improve the quality of life ... -
Employee Error: The Development, Validation, and Use of a Perceived Error Measure for Predicting Rumination, Burnout, and Counterproductive Work Behaviors
(East Carolina University, 2023-05-01)Errors are ubiquitous in organizations. Nonetheless, scholarly literature regarding workplace error has largely focused on low-rate catastrophic failures such as the Challenger, Columbia, and Chernobyl accidents. However, ... -
ENCOURAGING PREVENTIVE ACTION BY EMPLOYING EFFECTIVE RHETORIC IN PUBLIC COMMUNICATION OF THE ZIKA HAZARD AND ASSOCIATED RISKS
(East Carolina University, 2022-07-26)Threats from Zika and other emergent arboviruses (arthropod-borne viruses) often receive little scholarly attention across most disciplines thanks in no small part to the traditional view that most emergent disease discourse ... -
ENCOURAGING PREVENTIVE ACTION BY EMPLOYING EFFECTIVE RHETORIC IN PUBLIC COMMUNICATION OF THE ZIKA HAZARD AND ASSOCIATED RISKS
(East Carolina University, 2022-07-26)Threats from Zika and other emergent arboviruses (arthropod-borne viruses) often receive little scholarly attention across most disciplines thanks in no small part to the traditional view that most emergent disease discourse ... -
Enforced expression of HoxA9 in b-lineage all promotes survival and proliferation of leukemic cells
(East Carolina University, 2009)HoxA9 is frequently overexpressed in acute myeloid leukemia, myelodysplastic syndrome and a subset of acute lymphoblastic leukemia. In mouse models, HoxA9 has been shown to promote leukemogenesis. In spite of a seemingly ...